# Cannonball Lesions: A Case Report

**Authors:** Robin Sia

PMC · DOI: 10.7759/cureus.82554 · Cureus · 2025-04-19

## TL;DR

This paper presents a rare case of lung metastases caused by liver cancer, known as cannonball lesions.

## Contribution

The novelty is reporting hepatocellular carcinoma as a rare cause of cannonball lesions.

## Key findings

- Cannonball lesions were identified as metastases from hepatocellular carcinoma.
- This case highlights the importance of considering HCC in the differential diagnosis of cannonball lesions.

## Abstract

Cannonball lesions refer to multiple, well-defined, round pulmonary metastases seen on chest radiographs or CT scans. They are most commonly associated with hematogenous spread of malignancies, most frequently linked to renal cell carcinoma, choriocarcinoma, colorectal cancer, and breast cancer. We report a case of cannonball pulmonary metastases secondary to hepatocellular carcinoma (HCC).

## Linked entities

- **Diseases:** hepatocellular carcinoma (MONDO:0007256), renal cell carcinoma (MONDO:0005086), choriocarcinoma (MONDO:0003508), colorectal cancer (MONDO:0005575), breast cancer (MONDO:0004989)

## Full-text entities

- **Diseases:** Cannonball Lesions (MESH:D009059), pulmonary metastases (MESH:D009362), breast cancer (MESH:D001943), renal cell carcinoma (MESH:D002292), colorectal cancer (MESH:D015179), HCC (MESH:D006528), malignancies (MESH:D009369), choriocarcinoma (MESH:D002822)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12086501/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12086501/full.md

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Source: https://tomesphere.com/paper/PMC12086501