# Effects of Daily Kombu (Laminaria japonica) Intake on Body Composition, Blood Pressure, and Fecal Microbiota in Healthy Adult Japanese: A Randomized, Double‐Blind Study

**Authors:** Seiichiro Aoe, Hirofumi Ohtoshi, Fumiko Nakamura

PMC · DOI: 10.1002/fsn3.70298 · Food Science & Nutrition · 2025-05-19

## TL;DR

A study found that daily kombu intake in Japanese adults reduced body fat in men and improved gut microbiota in both men and women.

## Contribution

This study provides empirical evidence that kombu consumption may reduce body fat and alter gut microbiota in a controlled human trial.

## Key findings

- Body fat content and percentage decreased significantly in male kombu group compared to placebo.
- Kombu intake was associated with increased abundance of beneficial gut bacteria like Faecalibacterium and Agathobacter.
- Systolic blood pressure was lower in both genders in the kombu group.

## Abstract

Visceral obesity is considered to have a significant role in the development of metabolic syndrome; therefore, a diet that suppresses visceral fat accumulation could prevent its onset. The effects of kombu consumption on reducing body fat and associated changes in gut microbiota were assessed in a randomized, double‐blind, placebo‐controlled intervention study in Japanese adults. Random assignment of study subjects between two groups was performed, and over 12 weeks the test group consumed cookies containing boiled kombu powder, while the placebo group consumed cookies containing cellulose. Anthropometric profiles for each participant, including visceral fat area (VFA), were recorded at weeks 0, 6, and 12. Body fat content and percentage were significantly decreased in the male kombu group compared to the placebo group. Systolic blood pressure was significantly lower in males and females in the kombu group compared with the placebo group. Serum adiponectin levels in males were significantly higher in the kombu group compared with the placebo group. The concentration of serum thyroid hormones did not increase after 420 μg/day of iodine consumption throughout kombu intake. Significant increases in the abundances of genus Faecalibacterium, Bacteroides, Alistipes, and Agathobacter were observed in the kombu group compared to the placebo group. Changes in body fat content and percentage were significantly negatively correlated with the relative abundance of Agathobacter in men. The consumption of kombu powder, which is high in alginate, may help prevent body fat accumulation in male subjects and improve microbiota in both males and females.

The effects of kombu consumption on reducing body fat and associated changes in gut microbiota were assessed in a randomized, double‐blind, placebo‐controlled intervention study in Japanese adults. Body fat content and percentage were significantly decreased in the male kombu group compared to the placebo group. The consumption of kombu powder, which is high in alginate, may help prevent body fat accumulation in male subjects and improve microbiota in both males and females.

## Full-text entities

- **Genes:** ADIPOQ (adiponectin, C1Q and collagen domain containing) [NCBI Gene 9370] {aka ACDC, ACRP30, ADIPQTL1, ADPN, APM-1, APM1}
- **Diseases:** Visceral obesity (MESH:D056128), fat (MESH:D004620), metabolic syndrome (MESH:D024821)
- **Chemicals:** alginate (MESH:D000464)
- **Species:** Homo sapiens (human, species) [taxon 9606], Saccharina japonica (species) [taxon 88149], Alistipes (genus) [taxon 239759], Agathobacter (genus) [taxon 1766253], Faecalibacterium (genus) [taxon 216851], Bacteroides (genus) [taxon 816]

## Full text

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## Figures

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## References

36 references — full list in the complete paper: https://tomesphere.com/paper/PMC12086367/full.md

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Source: https://tomesphere.com/paper/PMC12086367