# Pancreas Divisum With Santorinicele: A Rare Cause of Recurrent Acute Pancreatitis

**Authors:** Fatimah A Alkhamis, Mohammed T Al Ali, Ahmet Aslan

PMC · DOI: 10.7759/cureus.82498 · Cureus · 2025-04-18

## TL;DR

This paper discusses a rare condition called Santorinicele, which can cause recurring pancreatitis and is often linked to pancreas divisum.

## Contribution

The paper presents a case of pancreatitis caused by pancreas divisum with Santorinicele and highlights the role of medical imaging in diagnosis.

## Key findings

- Santorinicele is a rare cause of recurrent acute pancreatitis.
- Medical imaging like MRI and MRCP is effective in diagnosing pancreatic duct abnormalities.
- Pancreas divisum combined with Santorinicele can lead to outflow obstruction of pancreatic secretions.

## Abstract

Santorinicele is a cystic dilatation at the terminal end of the pancreatic duct of Santorini, which is a rare condition mostly associated with pancreatic divisum. Patients with Santorinicele may present with recurrent pancreatitis due to elevated intraductal pressure and outflow obstruction of pancreatic secretions. Different imaging modalities, including magnetic resonance imaging (MRI) and magnetic resonance cholangiopancreatography (MRCP), are useful tools in identifying the causes of recurrent pancreatitis, and other pancreatic pathology and anatomical variants. Here, we present a case of recurrent acute pancreatitis caused by pancreas divisum with Santorinicele and discuss the role of medical imaging in the diagnosis.

## Linked entities

- **Diseases:** recurrent acute pancreatitis (MONDO:0018989)

## Full-text entities

- **Diseases:** Pancreas Divisum (MESH:D000092142), Acute Pancreatitis (MESH:D010195)
- **Chemicals:** Santorinicele (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12085784/full.md

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Source: https://tomesphere.com/paper/PMC12085784