# First-Trimester Radical Hysterectomy for Bulky Cervical Cancer: A Case Report on Oncologic and Reproductive Considerations

**Authors:** Munachiso I Ndukwe, Denisa Pohankova, Petr Halada, Jan Laco, Martin Stepan, Tatana Reslova, Petra Bretova, Dominik Karasek, Domink Habes, Adam Rezac, Igor Sirak

PMC · DOI: 10.7759/cureus.82486 · Cureus · 2025-04-18

## TL;DR

A woman with early-stage cervical cancer in her first trimester underwent radical hysterectomy after deciding to terminate her pregnancy.

## Contribution

This case report highlights individualized management of cervical cancer during pregnancy, balancing oncologic and reproductive considerations.

## Key findings

- Radical hysterectomy with pelvic lymphadenectomy was successfully performed at 10 weeks of gestation.
- The patient recovered well postoperatively and was advised to undergo adjuvant chemoradiotherapy.
- The case emphasizes the need for personalized treatment plans respecting maternal health and reproductive autonomy.

## Abstract

The management of cervical cancer during the first trimester of pregnancy requires a multidisciplinary approach that considers medical, psychological, and social factors. This report details the case of a patient diagnosed preoperatively with bulky early-stage cervical cancer at nine weeks of gestation, during an evaluation initially intended for pregnancy termination. While definitive chemoradiotherapy is the standard treatment for early-stage bulky cervical tumors, the treatment strategy, in this case, was influenced by the patient’s decision to terminate the pregnancy without delay. A radical hysterectomy with pelvic lymphadenectomy was successfully performed at 10 weeks of gestation. The patient experienced an uneventful postoperative recovery and was subsequently advised to undergo adjuvant chemoradiotherapy. This case underscores the importance of an individualized management plan that prioritizes maternal health while respecting reproductive rights and patient autonomy.

## Linked entities

- **Diseases:** cervical cancer (MONDO:0002974)

## Full-text entities

- **Diseases:** Cervical Cancer (MESH:D002583)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12085773/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12085773/full.md

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Source: https://tomesphere.com/paper/PMC12085773