# Successful Treatment of an Extensive Deep Vein Thrombosis in the Lower Left Extremity Through Thrombectomy and Endovascular Stenting: Role of May-Thurner Syndrome in Differential Diagnoses

**Authors:** Hong Thoai Nguyen, Chau Dang, Juveriya Yasmeen, Pham Thao Vy Le, Lac Han Nguyen

PMC · DOI: 10.7759/cureus.82468 · Cureus · 2025-04-17

## TL;DR

A 45-year-old woman with no prior medical history was successfully treated for deep vein thrombosis caused by May-Thurner syndrome using thrombectomy and stenting.

## Contribution

This case demonstrates the effectiveness of endovascular treatment for symptomatic May-Thurner syndrome-related DVT.

## Key findings

- Mechanical thrombectomy and stenting successfully treated extensive DVT in a patient with May-Thurner syndrome.
- Two years post-treatment, the patient had chronic venous changes but no DVT recurrence.
- Early diagnosis and endovascular management improved outcomes in this MTS case.

## Abstract

May-Thurner syndrome (MTS) is a vascular condition caused by extrinsic compression of the left common iliac vein by the right common iliac artery, predisposing patients to deep vein thrombosis (DVT). Though often asymptomatic, MTS can present with unilateral leg swelling and pain, particularly in young women without traditional risk factors. We present the case of a 45-year-old woman who developed acute left lower extremity DVT without prior medical history or provoking factors. Imaging confirmed extensive thrombosis and revealed complete iliac vein compression consistent with MTS. The patient underwent successful mechanical thrombectomy, stenting, and balloon angioplasty, followed by long-term anticoagulation. Two years post-intervention, she exhibited chronic venous changes but no recurrent DVT. This case highlights the importance of early diagnosis and endovascular management in symptomatic MTS to optimize outcomes and reduce long-term complications.

## Linked entities

- **Diseases:** May-Thurner syndrome (MONDO:0043361)

## Full-text entities

- **Diseases:** pain (MESH:D010146), DVT (MESH:D020246), thrombosis (MESH:D013927), leg swelling (MESH:D004487), MTS (MESH:D062108)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12085234/full.md

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Source: https://tomesphere.com/paper/PMC12085234