# Diagnostic values of noradrenaline administered dose, procalcitonin (PCT) and blood lactic acid for septic shock

## TL;DR

This study examines how noradrenaline doses, procalcitonin, and blood lactic acid levels relate to survival in septic shock patients.

## Contribution

The study evaluates noradrenaline dosing impact and identifies biomarkers associated with survival in septic shock.

## Key findings

- Higher noradrenaline doses were associated with increased mortality in septic shock patients.
- Procalcitonin and blood lactic acid levels were significantly different between surviving and non-surviving patients.
- Clinical data and biomarkers can help predict outcomes in sepsis/septic shock treatment.

## Abstract

Sepsis/septic shock is a life-threatening condition that requires prompt and effective treatment. Noradrenaline is a widely used vasopressor to manage septic shock, but its optimal dosage remains unclear. This study aimed to investigate the effects of noradrenaline doses on the prognosis of patients with sepsis/septic shock and identify the influencing factors for patient survival.

A retrospective study was conducted on 126 patients with sepsis/septic shock who received noradrenaline treatment in the intensive care unit (ICU). Patients were divided into survival (n=91) and death (n=35) groups. Clinical data, laboratory results, and noradrenaline doses were collected and compared between the two groups.