# Adrenal Ganglioneuroma Masquerading as a Suspicious Adrenal Incidentaloma: A Case Report and Review of the Literature

**Authors:** Zein B Sheikh, Nariman A Nawar, Abdulrahman S Alamri

PMC · DOI: 10.7759/cureus.82455 · Cureus · 2025-04-17

## TL;DR

A rare benign adrenal tumor was mistaken for a suspicious tumor in a 58-year-old woman, highlighting the need for further testing to avoid unnecessary surgery.

## Contribution

This case report adds to the limited literature on adrenal ganglioneuromas and their diagnostic challenges.

## Key findings

- Adrenal ganglioneuromas can mimic malignant tumors on imaging.
- The tumor in this case was hormonally inactive and confirmed benign post-surgery.

## Abstract

Adrenal ganglioneuromas are rare tumors. Although benign in nature, radiographic features are non-diagnostic and can be suspicious for malignant tumors, necessitating surgical adrenalectomy for histopathologic diagnosis. Most are discovered incidentally, and are hormonally inactive. Workup to exclude functional tumors is warranted. We describe a case of a 58-year-old female patient with an adrenal ganglioneuroma masquerading as a suspicious adrenal incidentaloma on imaging.

## Full-text entities

- **Diseases:** Adrenal Ganglioneuroma (MESH:D005729), Adrenal Incidentaloma (MESH:C538238), malignant (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12085163/full.md

## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12085163/full.md

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Source: https://tomesphere.com/paper/PMC12085163