# A Case of Low T1 Mapping Values in Myocardial Calcifications in a Patient With End-Stage Renal Disease

**Authors:** Ahmed Abdelmonem, Ahmed S Negm, Subhi Al'Aref, Kedar Jambhekar

PMC · DOI: 10.7759/cureus.82431 · Cureus · 2025-04-17

## TL;DR

This paper presents a rare case linking myocardial calcifications with low T1 values in a patient with kidney failure.

## Contribution

The case highlights a novel association between myocardial calcifications and low T1 mapping values in end-stage renal disease.

## Key findings

- A 24-year-old female with end-stage renal disease showed decreased T1 values.
- Myocardial calcifications were associated with low T1 mapping values in this patient.
- This case adds to limited prior evidence linking calcifications and low T1 values.

## Abstract

Cardiac MRI is the gold standard in diagnosing many cardiac pathologies. T1 mapping, a novel cardiac MRI sequence, provides precise assessment and characterization of myocardial tissue. Low T1 values have been reported in specific entities, including Fabry disease and iron overload.

We report a case of decreased T1 values with diffuse myocardial calcifications in a 24-year-old female with end-stage renal disease. This case provides valuable new insights into T1 mapping, particularly regarding the association between myocardial calcifications and low T1 values, a connection that has only been reported in a single prior study.

## Linked entities

- **Diseases:** end-stage renal disease (MONDO:0004375)

## Full-text entities

- **Diseases:** Fabry disease (MESH:D000795), Myocardial Calcifications (MESH:D002114), iron overload (MESH:D019190), End-Stage Renal Disease (MESH:D007676)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12085066/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12085066/full.md

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Source: https://tomesphere.com/paper/PMC12085066