# Diffuse Large B-Cell Lymphoma Presenting With Multiple Episodes of Acute Pancreatitis

## TL;DR

A rare case of diffuse large B-cell lymphoma causing multiple episodes of acute pancreatitis is reported, highlighting the need for thorough diagnostic evaluation.

## Contribution

The paper presents a rare clinical case linking DLBCL to recurrent acute pancreatitis.

## Key findings

- DLBCL can present as multiple episodes of acute pancreatitis.
- A broad differential diagnosis is crucial when common causes of pancreatitis are ruled out.

## Abstract

Gallstones and alcohol use are the most common causes of acute pancreatitis. When these etiologies are effectively ruled out, some less frequent causes include hypertriglyceridemia, medications, autoimmune conditions, and malignancy. Although rare, lymphoma infiltrating the pancreas can present with episodes of acute pancreatitis. In this report, we discuss a rare case of a patient who presented with multiple episodes of acute pancreatitis due to diffuse large B-cell lymphoma (DLBCL) infiltrating the pancreas. In the process, we emphasize the importance of maintaining a broad differential and performing the appropriate diagnostic evaluation when the immediate cause of acute pancreatitis is unclear.