# Analysis of Overactive Bladder Symptom Score Improvement in Lower Urinary Tract Symptom Patients During Behavioral Therapy While Using the Smartphone Application "USAPO"

**Authors:** Kosuke Mikami, Kanya Kaga, Tomohiko Ichikawa

PMC · DOI: 10.7759/cureus.82406 · Cureus · 2025-04-16

## TL;DR

A smartphone app called USAPO was tested to see if it helps improve bladder symptoms during behavioral therapy, but overall no significant improvement was found.

## Contribution

The study evaluates the effectiveness of a smartphone app in improving urinary symptoms through sustained behavioral therapy.

## Key findings

- No significant overall change in Overactive Bladder Symptom Score (OABSS) was observed after using the USAPO app.
- A subset of patients showed a one-point improvement in OABSS, with significant differences in symptom severity compared to non-responders.
- Age showed a borderline statistically significant trend in patients who improved their OABSS.

## Abstract

Introduction: According to Japanese lower urinary tract symptom (LUTS) guidelines, behavioral therapy is recommended as a first-line treatment for LUTS. However, the guidance provided during outpatient visits alone may not be sufficiently effective, as patients are unlikely to change their behavior. This study aimed to evaluate the changes in urinary storage symptoms after sustained intervention using a mobile application.

Methods: Changes in Overactive Bladder Symptom Score (OABSS) resulting from the sustained intervention were assessed among users of the mobile application "USAPO."

Results: A total of 139 patients were included in this study. The OABSS before and after using USAPO was 2.03±2.42 and 2.25±2.826 points, respectively, with no significant difference (p=0.2194). The group with at least a one-point improvement in OABSS showed a statistically significant trend in age (p=0.055) and a statistically significant difference in the severity of urinary storage symptoms compared to the non-responding group (p<0.0001).

Conclusions: Although no overall change in OABSS was observed with the introduction of USAPO, a subset of patients may benefit from its use.

## Linked entities

- **Diseases:** Overactive Bladder (MONDO:0006624)

## Full-text entities

- **Diseases:** Lower Urinary Tract (MESH:D014570), Overactive Bladder Symptom (MESH:D053201), urinary storage (MESH:D014548)
- **Chemicals:** USAPO (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12084726/full.md

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Source: https://tomesphere.com/paper/PMC12084726