# A case of abnormal hypertension and Takotsubo syndrome caused by adrenal hemostasis using an electric scalpel: a case report

**Authors:** Tsutomu Suzuki, Naoko Kubo, Kei Kamiutsuri

PMC · DOI: 10.1186/s40981-025-00791-y · JA Clinical Reports · 2025-05-16

## TL;DR

A 74-year-old woman developed abnormal hypertension and Takotsubo syndrome during adrenal surgery using an electric scalpel, highlighting the need for vigilance in managing hemodynamic changes.

## Contribution

This case report highlights a rare complication of adrenal electrocauterization leading to Takotsubo syndrome.

## Key findings

- Abnormal hypertension during adrenal electrocauterization led to Takotsubo syndrome in a 74-year-old patient.
- Postoperative echocardiography showed apical hypokinesis and basal hyperkinesis with reduced ejection fraction.
- The patient's heart function improved significantly within a month with no residual wall asynergy.

## Abstract

Although intraoperative adrenal hemostasis by cauterization can cause abnormal hypertension, hemodynamic condition is usually normalized in a few minutes without any postoperative complications. We present a rare case of abnormal hypertension caused by adrenal hemostasis using an electric scalpel, which resulted in cardiac dysfunction: Takotsubo syndrome.

A 74-year-old woman received open hepatectomy for a hepatic tumor. During adrenal electrocauterization, abnormal hypertension and tachycardia suddenly occurred. Although the blood pressure returned to the baseline in a few minutes by nicardipine and landiolol, postoperative echocardiography revealed apical hypokinesis and basal hyperkinesis of the left ventricular wall with a decreased ejection fraction of 50%. Along with no coronary artery stenosis by CT angiography, a diagnosis of Takotsubo syndrome was made. Postoperative course was uneventful; ejection fraction increased to 69% with no obvious left ventricular wall asynergy at 1-month postoperative follow-up.

Adrenal cauterization during surgery may cause abnormal hypertension by release of excessive catecholamines, and potentially lead to Takotsubo syndrome. Anesthesiologists should be prepared to respond quickly to any unexpected changes in hemodynamics.

## Linked entities

- **Diseases:** Takotsubo syndrome (MONDO:0019018)

## Full-text entities

- **Diseases:** coronary artery stenosis (MESH:D023921), Takotsubo syndrome (MESH:D054549), hepatic tumor (MESH:D009369), cardiac dysfunction (MESH:D006331), abnormal hypertension (MESH:D006973), tachycardia (MESH:D013610), hyperkinesis (MESH:D006948)
- **Chemicals:** landiolol (MESH:C077049), catecholamines (MESH:D002395), nicardipine (MESH:D009529)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12084443