# A bi-institutional observational study comparing short-term and long-term outcome of operative and non-operative management of clinical and radiological flail chest injuries

**Authors:** Eva-Corina Caragounis, Monika Fagevik Olsén, Lena Sandström, Rauni Rossi Norrlund, Lovisa Strömmer, Hans Granhed

PMC · DOI: 10.1186/s13049-025-01400-8 · Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine · 2025-05-15

## TL;DR

This study compared surgical and non-surgical treatments for flail chest injuries and found no long-term benefits of surgery, though it reduced pneumonia and early pain.

## Contribution

The study provides new evidence on the long-term outcomes of surgical versus non-surgical flail chest management in trauma patients.

## Key findings

- Operative management did not reduce the need for mechanical ventilation or ICU stay.
- Surgery was linked to lower pneumonia rates and less early pain despite more severe trauma in operated patients.
- No significant differences in pain, function, or quality of life were found after one year.

## Abstract

Operative management of chest wall injuries requiring ventilatory support has been shown to decrease the time spent on ventilator. The main purpose of this study was to investigate whether operative management reduces the need for mechanical ventilation and the impact of surgery on long-term outcome concerning pain, lung function and movement.

This is a bi-institutional prospective observational study comparing operative (Op) and non-operative (Non-Op) management of adult trauma patients with flail chest injuries. Data on the need for and LOS in intensive care (ICU), on mechanical ventilator (MV), and in hospital, and incidence of pneumonia and tracheostomy was collected. Clinical follow-up after six weeks, six months and one year concerning lung function, CT-lung volume, physical function, pain, and quality of life (QoL) was performed.

There was no difference in the need for (29%) and LOS on MV and in ICU between the Op and Non-Op groups. Chest wall surgery was performed 4 days (range 2–14) post trauma and associated with a longer hospital LOS. Pneumonia was more common in the Non-Op group (37% vs. 18%, p = 0.003). Fifty patients in the Op group and 38 patients in the Non-Op group were enrolled in a follow-up where Non-Op group experienced more pain in the first six months and had a higher daily dose of oral morphine during the first six weeks post trauma. The best residual lung function and CT-lung volume was seen in patients managed with muscle-sparing surgery without thoracotomy. No considerable difference in pain, physical activity, physical function and QoL were seen between the groups after one year.

Operative management of flail chest injuries did not decrease the need for mechanical ventilation or the length of stay in ICU. Operating on non-ventilated patients may increase the length of hospital stay depending on day of surgery. Surgery was associated with a decreased incidence of pneumonia, less pain and subjective symptoms the first months’ post-trauma despite operated patients being older and with more severe trauma, but after one year there were no significant differences between the groups. Operative technique may influence outcome and should be studied further.

ClinicalTrials.gov: NCT02132416, 7 May 2014.

## Linked entities

- **Diseases:** pneumonia (MONDO:0005249)

## Full-text entities

- **Diseases:** Extra-thoracic injuries (MESH:D013898), Flail chest (MESH:D005409), fractured (MESH:D050723), pneumothorax (MESH:D011030), anxiety (MESH:D001007), tenderness (MESH:D063806), Injury (MESH:D014947), spinal injury (MESH:D013124), AIS (MESH:C538175), lung contusion (MESH:D008171), empyema (MESH:D004653), pain (MESH:D010146), respiratory insufficiency (MESH:D012131), chest infection (MESH:D002637), neurological and/or musculoskeletal disease (MESH:D009140), hemothorax (MESH:D006491), sternal flail (MESH:C537489), Pneumonia (MESH:D011014), depression (MESH:D003866), lung laceration (MESH:D022125), MV (MESH:D053717), Head AIS (MESH:D006259), thoracic trauma (MESH:D013896), TBI (MESH:D000070642), shoulder injured (MESH:D000070599), displaced (MESH:D006617), PEF (MESH:C564040), DRI (MESH:C566784), SSRF (MESH:D012253), TEDA (MESH:D000699), bleeding (MESH:D006470), breathlessness (MESH:D004417), rigidity (MESH:D009127)
- **Chemicals:** morphine (MESH:D009020), paracetamol (MESH:D000082), Extracorporeal (-), op (MESH:C572232)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

2 references — full list in the complete paper: https://tomesphere.com/paper/PMC12082970/full.md

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Source: https://tomesphere.com/paper/PMC12082970