# Anesthesia Management Using Remimazolam in A Patient With Bernard‐Soulier Syndrome: A Case Report

**Authors:** Tomoharu Shakuo, Yusuke Ishida, Daiki Sugawara, Masato Ryo, Haruko Okazaki, Katsunori Oe

PMC · DOI: 10.1002/ccr3.70519 · Clinical Case Reports · 2025-05-16

## TL;DR

This case report shows that remimazolam can be safely used for anesthesia in a patient with Bernard-Soulier syndrome, a rare blood disorder.

## Contribution

The paper demonstrates the safe application of remimazolam in a patient with Bernard-Soulier syndrome, offering a new anesthetic option for this condition.

## Key findings

- Remimazolam was used successfully for anesthesia in a patient with Bernard-Soulier syndrome.
- No adverse effects related to platelet function were observed during or after the procedure.

## Abstract

Bernard‐Soulier syndrome (BSS) is a platelet dysfunction disorder characterized by massive thrombocytopenia and a lack of platelet aggregation. Remimazolam, a short‐acting benzodiazepine sedative, is believed to have minimal effects on platelets. Here, we report the safe use of remimazolam for anesthesia management in a patient with BSS.

## Linked entities

- **Chemicals:** remimazolam (PubChem CID 9867812)
- **Diseases:** Bernard-Soulier syndrome (MONDO:0009276)

## Full-text entities

- **Diseases:** BSS (MESH:D001606), thrombocytopenia (MESH:D013921), platelet aggregation (MESH:D001791)
- **Chemicals:** Remimazolam (MESH:C522201), benzodiazepine (MESH:D001569)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12082809/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12082809/full.md

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Source: https://tomesphere.com/paper/PMC12082809