# TAVI in Complex Dual-Level Obstruction: A Case of Severe Aortic Stenosis and Subaortic Membrane

**Authors:** Salem Assiri, Mohammed S. Alshammakh, Sultan M. Alzahrani, Moath Said Alfawara, Khaled Al-Shaibi

PMC · DOI: 10.14797/mdcvj.1539 · Methodist DeBakey Cardiovascular Journal · 2025-05-12

## TL;DR

This case study shows how TAVI can be successfully used in patients with both severe aortic stenosis and a subaortic membrane.

## Contribution

The study demonstrates TAVI's viability in complex dual-level obstruction cases where surgery is not an option.

## Key findings

- Multimodal imaging enabled successful TAVI in a high-risk patient with dual-level obstruction.
- TAVI is a viable alternative to surgery for patients with severe aortic stenosis and subaortic membrane.
- The approach avoids the need for open surgery in non-surgical candidates.

## Abstract

This case addresses the challenges of treating patients with both severe aortic stenosis and subaortic stenosis. In this combined condition, transcatheter aortic valve implantation (TAVI) remains an off-label application, particularly in the presence of a subaortic membrane.

Our multimodal imaging approach that incorporates echocardiography, cardiac computed tomography, and fluoroscopic guidance demonstrates the successful application of TAVI in a high-risk clinical scenario. The results underscore the potential of TAVI as a viable alternative to traditional surgical aortic valve replacement for patients with dual-level obstruction who are not candidates for open surgery.

## Linked entities

- **Diseases:** aortic stenosis (MONDO:0042981)

## Full-text entities

- **Diseases:** subaortic stenosis (MESH:D021922), Aortic Stenosis (MESH:D001024)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12082459/full.md

## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12082459/full.md

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Source: https://tomesphere.com/paper/PMC12082459