# “Hyperkinetic” and “Hypokinetic”: Is There a Need for a Third Category (i.e., “Mixed”)?

**Authors:** Sara M. Schaefer, Elan D. Louis

PMC · DOI: 10.5334/tohm.997 · Tremor and Other Hyperkinetic Movements · 2025-05-13

## TL;DR

This paper argues for adding a 'mixed' category to classify movement disorders that show both hyperkinetic and hypokinetic features.

## Contribution

The paper proposes a new 'mixed' category to better classify complex movement disorders.

## Key findings

- Traditional two-category classification fails to capture the complexity of some movement disorders.
- Movement disorders like ataxia and rigidity show mixed hyper- and hypokinetic features.
- A third 'mixed' category would improve classification accuracy.

## Abstract

Terminology in the field of movement disorders has evolved multiple times over the years. Traditionally, classification schema have utilized a two-category approach, with a hyper- and hypokinetic branchpoint as the first step towards describing movement disorders and elucidating phenomenological diagnoses. However, this terminology falls short, as it does not adequately capture the complexity of several abnormalities of movement- including ataxia and rigidity- at the electrophysiologic and phenotypic levels. Rather, these movement disorders are characterized by mixed hyper- and hypokinetic phenomena. We propose a third category, “mixed”, which would optimally classify the full range of movements.

## Full-text entities

- **Diseases:** hyper- and hypokinetic (MESH:D004401), rigidity (MESH:D009127), movement disorders (MESH:D009069), abnormalities of movement (MESH:D004409), Hyperkinetic (MESH:D006948), ataxia (MESH:D001259)

## Full text

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## References

15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12082446/full.md

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Source: https://tomesphere.com/paper/PMC12082446