# Combining meta reinforcement learning with neural plasticity mechanisms for improved AI performance

**Authors:** Liu Liu, Zhifei Xu

PMC · DOI: 10.1371/journal.pone.0320777 · PLOS One · 2025-05-15

## TL;DR

This paper combines meta reinforcement learning with a brain-inspired learning rule to improve AI performance in games.

## Contribution

A novel hybrid model combining MRL and STDP is introduced, showing improved learning and adaptability in AI agents.

## Key findings

- The MRL-STDP model achieved a 40% increase in learning efficiency compared to traditional methods.
- Adaptability improved by 35% in changing game conditions.
- The hybrid model outperformed Q-learning and DQN baselines in cross-game generalization.

## Abstract

This research explores the potential of combining Meta Reinforcement Learning (MRL) with Spike-Timing-Dependent Plasticity (STDP) to enhance the performance and adaptability of AI agents in Atari game settings. Our methodology leverages MRL to swiftly adjust agent strategies across a range of games, while STDP fine-tunes synaptic weights based on neuronal spike timings, which in turn improves learning efficiency and decision-making under changing conditions. A series of experiments were conducted with standard Atari games to compare the hybrid MRL-STDP model against baseline models using traditional reinforcement learning techniques like Q-learning and Deep Q-Networks. Various performance metrics, including learning speed, adaptability, and cross-game generalization, were evaluated. The results show that the MRL-STDP approach significantly accelerates the agent’s ability to reach competitive performance levels, with a 40% boost in learning efficiency and a 35% increase in adaptability over conventional models.

## Full-text entities

- **Diseases:** DQN (MESH:D011778), RL (MESH:D007859), STDP (MESH:D031261)
- **Chemicals:** Atari (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** A3C

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12080787/full.md

## Figures

10 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12080787/full.md

## References

59 references — full list in the complete paper: https://tomesphere.com/paper/PMC12080787/full.md

---
Source: https://tomesphere.com/paper/PMC12080787