# Management of Rhinomaxillary Mucormycosis: A Case Report

**Authors:** Sandeep Khandaitkar, Komal Harde, Sharjeel H Khan, Gagandeep Lamba

PMC · DOI: 10.7759/cureus.82299 · Cureus · 2025-04-15

## TL;DR

A 45-year-old woman developed a rare fungal infection in her mouth after a tooth extraction, which was successfully treated with surgery and antifungal therapy.

## Contribution

Highlights the rare occurrence of mucormycosis in an immunocompetent patient and the importance of timely diagnosis and treatment.

## Key findings

- Mucormycosis was confirmed postoperatively despite initial diagnosis of aspergillosis.
- Aggressive surgical and antifungal treatment led to successful recovery.
- Emphasizes the need for comprehensive management in mucormycosis cases.

## Abstract

This case report describes a rare occurrence of palatal mucormycosis in a 45-year-old immunocompetent female patient who developed black discoloration of the palate following a tooth extraction. Initial diagnostic investigations and superficial biopsy revealed aspergillosis; however, further postoperative histopathological examination confirmed mucormycosis. Aggressive surgical intervention, including maxillectomy, alveolectomy, and functional endoscopic sinus surgery, combined with targeted antifungal therapy, facilitated successful treatment. The importance of timely diagnosis and comprehensive management in mucormycosis cases, even among immunocompetent patients, is highlighted.

## Linked entities

- **Diseases:** mucormycosis (MONDO:0019136), aspergillosis (MONDO:0005657)

## Full-text entities

- **Genes:** CD4 (CD4 molecule) [NCBI Gene 920] {aka CD4mut, IMD79, Leu-3, OKT4D, T4}
- **Diseases:** Mucorales (MESH:D009091), chikungunya (MESH:D065632), palatal lesions (MESH:D002972), black discoloration of the palate (MESH:D014075), invasive (MESH:D009361), hematologic malignancies (MESH:D019337), hyperglycemia (MESH:D006943), bony (MESH:D018213), COVID-19 (MESH:D000086382), aspergillosis (MESH:D001228), diabetes (MESH:D003920), necrotic (MESH:D009336), fungal (MESH:D009181), infectious disease (MESH:D003141), infection (MESH:D007239), dengue fever (MESH:D003715), inflammation (MESH:D007249), bacterial infections (MESH:D001424), pain (MESH:D010146)
- **Chemicals:** Blankophor (-), KOH (MESH:C029943), Amphotericin B (MESH:D000666), chitin (MESH:D002686), posaconazole (MESH:C101425), triazole (MESH:D014230)
- **Species:** Homo sapiens (human, species) [taxon 9606], Human immunodeficiency virus (species) [taxon 12721], Mucorales (pin molds, order) [taxon 4827], Aspergillus (genus) [taxon 5052]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12080622/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12080622/full.md

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Source: https://tomesphere.com/paper/PMC12080622