# The use of intraventricular vancomycin in subacute brain abscess in an adolescent male: A case report

## TL;DR

A 12-year-old boy with multiple brain abscesses was successfully treated with a single intraventricular dose of vancomycin after conventional treatments failed.

## Contribution

This is the first reported use of intraventricular vancomycin in a pediatric patient for treating brain abscesses.

## Key findings

- A single intraventricular dose of vancomycin resolved multiple brain abscesses in a 12-year-old male.
- The patient showed symptom alleviation after conventional treatments failed.
- The case highlights the need for standardized dosing guidelines for this rare intervention.

## Abstract

Brain abscess is a serious condition in children, leading to rapid deterioration, and permanent neurological damage associated with significant morbidity and mortality. Current management protocols for brain abscesses focus on intravenous antibiotics and surgical excision and drainage.

A 12-year-old adolescent male who had headache and photophobia and was diagnosed with multiple brain abscesses and was refractory to conventional medical and neurosurgical intervention. A single dose of 10 mg vancomycin was administered through endo-ventricular drain, resulting in resolution of abscesses and alleviation of symptoms.

We describe the first instance of intraventricular vancomycin use in the pediatric age group for the treatment of multiple brain abscesses. Given the variability in dosing reported in the literature, our case report warrants further studies to standardize dosage for this rare intervention.