# Asymptomatic Ileal Intussusception: A Rare Twist in a Marginal B-cell Lymphoma

## TL;DR

A rare case of marginal B-cell lymphoma presented with ileal intussusception and was successfully treated with surgery and H. pylori eradication.

## Contribution

Highlights an atypical presentation of marginal zone B-cell lymphoma with ileocecal intussusception and successful treatment outcomes.

## Key findings

- A 75-year-old male with marginal zone B-cell lymphoma presented with ileal intussusception.
- Right hemicolectomy and H. pylori eradication led to asymptomatic remission with no recurrence.
- Chronic atrophic gastritis and Helicobacter pylori were additional findings in the patient.

## Abstract

A 75-year-old male patient with a history of type 2 diabetes, hypertension, interstitial pneumonitis, and gastroesophageal reflux disease underwent a screening colonoscopy that revealed a 3-4 cm ulcerated ileal tumor. Subsequent diagnostic evaluations, including endoscopy and contrast-enhanced CT, identified additional findings of chronic atrophic gastritis with Helicobacter pylori and ileocecal intussusception. Histopathological analysis confirmed a marginal zone B-cell lymphoma with CD20+ expression and negative surgical margins following a right hemicolectomy. H. pylori eradication was successful, and the patient remains asymptomatic with no evidence of recurrence. It can present atypically, including intussusception. Early detection and appropriate management are crucial for achieving favorable outcomes.