# Endocuff‐Assisted Colonoscopy for Identifying Sessile Serrated Polyps and Adenomas During Routine Colorectal Cancer Screening: A Retrospective Cohort Study

**Authors:** Ammad Javaid Chaudhary, Muhammad Saad Faisal, Abdullah Sohail, Hope Baldwin, Kevin Harris, Muhammad Shahzil, Muhammad Salman Faisal, Avi Toiv, Keith Mullins, Suraj Suresh

PMC · DOI: 10.1002/jgh3.70173 · JGH Open: An Open Access Journal of Gastroenterology and Hepatology · 2025-05-14

## TL;DR

This study found that using an Endocuff during colonoscopies helps detect more difficult-to-see polyps without increasing procedure time.

## Contribution

The study provides evidence that Endocuff-assisted colonoscopy improves detection of sessile serrated polyps during routine screening.

## Key findings

- EAC significantly increased the detection rate of sessile serrated polyps compared to conventional colonoscopy.
- There was no significant difference in tubular adenoma detection rates between the two methods.
- EAC had a lower success rate for ileal intubation compared to conventional colonoscopy.

## Abstract

Polyps located in less accessible areas of the colon, such as inner curves of flexures, are often difficult to visualize. Colonoscope attachments such as the Endocuff have been developed to improve the visualization of these polyps. We aimed to assess the utility of Endocuff‐assisted colonoscopy (EAC) in the detection of tubular adenomas and sessile serrated polyps (SSP) compared to conventional colonoscopy during routine colorectal cancer screening.

This retrospective cohort study included patients who underwent colorectal cancer screening with either conventional colonoscopy or EAC between November 2022 and March 2023. The primary outcomes were SSP and tubular adenoma detection rates. Secondary outcomes included total procedure time, cecal intubation time, and ileal intubation rates.

Of the 435 patients included, 189 (43%) underwent EAC, and 246 (57%) underwent conventional colonoscopy. The mean ± standard deviation number of polyps detected was 1.7 ± 2.2, the mean procedure time was 18.7 ± 7.5 min, and the mean cecal intubation time was 4.4 ± 3.3 min, with no significant differences between groups. A smaller proportion of patients in the EAC group had successful ileal intubation (14% vs. 55%; p < 0.01). The tubular adenoma detection rate was similar between EAC and conventional colonoscopy (41% vs. 39%; p = 0.70), but the SSP detection rate was significantly higher with EAC (16% vs. 8.5%; p < 0.01).

EAC may enhance the detection of difficult‐to‐visualize SSPs during screening colonoscopies without affecting overall procedure time. However, physicians should consider the examination indication when selecting EAC, as ileal intubation may be more challenging.

## Linked entities

- **Diseases:** colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** Adenomas (MESH:D000236), diarrhea (MESH:D003967), cancer (MESH:D009369), abdominal pain (MESH:D015746), CRC (MESH:D015179), adenomatous polyp (MESH:D018256), dysplastic (MESH:D004416), diverticulosis (MESH:D004240), mucosal injuries (MESH:D052016), mucosal trauma (MESH:D014947), inflammatory bowel disease (MESH:D015212), melena (MESH:D008551), Polyps (MESH:D011127), blood loss (MESH:D016063), bleeding (MESH:D006470), precancerous lesions (MESH:D011230), adenomatous (MESH:D011125), serrated lesions (MESH:D009059), pre (MESH:D058246)
- **Chemicals:** EAC (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

26 references — full list in the complete paper: https://tomesphere.com/paper/PMC12078195/full.md

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Source: https://tomesphere.com/paper/PMC12078195