# A case of Crohn's disease in a patient with megacystis microcolon intestinal hypoperistalsis syndrome

## TL;DR

A rare case of a patient with both Crohn's disease and a congenital intestinal disorder is reported, highlighting unusual clinical overlap.

## Contribution

This case report presents a unique co-occurrence of MMIHS and inflammatory bowel disease, expanding clinical understanding.

## Key findings

- A patient with MMIHS was diagnosed with Crohn's disease, a rare combination.
- The case suggests potential for chronic inflammation in MMIHS to contribute to inflammatory bowel disease.
- This report adds to the limited literature on long-term complications in MMIHS survivors.

## Abstract

Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a rare congenital condition resulting in symptoms of bowel and bladder pseudo‐obstruction. It carries severe morbidity and mortality; a minority of patients survive to adulthood. Recurrent bowel surgeries, small intestinal bacterial overgrowth, and slowed intestinal transit in MMIHS could serve as potential risk factors for chronic inflammation of the intestinal mucosa, which has been associated with risk of inflammatory bowel disease. In this case report, we detail the unusual presentation of a patient diagnosed with both MMIHS and inflammatory bowel disease.