# SPNing our wheels—Pancreatic solid pseudopapillary neoplasm as an extraluminal etiology of persistent duodenal ulceration

**Authors:** Kanak V. Kennedy, Jibraan A. Fawad, Y. Dana Neugut, Doris Valenzuela‐Araujo, Alexander Coe, Tricia R. Bhatti, Michael Acord, Michael D. Manfredi, Petar Mamula, Kathleen M. Loomes, Jefferson N. Brownell

PMC · DOI: 10.1002/jpr3.70003 · JPGN Reports · 2025-02-25

## TL;DR

A rare pancreatic tumor was found to cause persistent duodenal ulcers in a child, highlighting the need to consider extraluminal causes in such cases.

## Contribution

This case report identifies a pancreatic solid pseudopapillary neoplasm as a rare extrinsic cause of duodenal ulceration in a pediatric patient.

## Key findings

- A pancreatic head solid pseudopapillary neoplasm presented with duodenal ulceration and recurrent upper GI bleeding.
- Extraluminal etiologies should be considered when duodenal ulcers recur or progress without other known causes.

## Abstract

Pediatric upper gastrointestinal (GI) bleeding secondary to duodenal ulceration is a potentially serious and life‐threatening condition with a broad differential diagnosis. We present a pediatric case of a pancreatic head solid pseudopapillary neoplasm (SPN) presenting with duodenal ulceration and recurrent upper GI bleeding. This case highlights pancreatic SPNs as a rare extrinsic cause of duodenal ulceration. Recurrence and progression in size and extent of a duodenal ulceration in the absence of other inciting factors should raise suspicion for an extraluminal etiology.

## Full-text entities

- **Diseases:** GI bleeding (MESH:D006471), duodenal ulceration (MESH:D004381), head (MESH:D006258), Pancreatic solid pseudopapillary neoplasm (MESH:D010190), SPN (MESH:D009369)

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12078036/full.md

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Source: https://tomesphere.com/paper/PMC12078036