# Kyphoplasty of a C2 Body Intraosseous Schwannoma: A Case Report

**Authors:** Michael Rodman, Diana Fang, Majid Khan, Qingqing Wu

PMC · DOI: 10.7759/cureus.82264 · Cureus · 2025-04-14

## TL;DR

A rare case of a benign spinal tumor treated with kyphoplasty is reported, highlighting the importance of considering such tumors in ambiguous bone lesions.

## Contribution

This is the second reported case of kyphoplasty used for an intraosseous schwannoma, offering a treatment and diagnostic approach for rare spinal tumors.

## Key findings

- Intraosseous schwannoma was diagnosed after biopsy and kyphoplasty of a C2 vertebral lesion.
- The histologic appearance confirmed the benign nature of the tumor, resolving diagnostic uncertainty.
- Kyphoplasty can serve both diagnostic and therapeutic roles in managing rare spinal tumors.

## Abstract

We report a case of a 75-year-old male with an incidental and indeterminate lytic lesion of the C2 vertebral body. After rapid enlargement over 16 months, persistent neck pain, and concern for underlying occult malignancy, the patient underwent lesion biopsy and simultaneous balloon kyphoplasty. Histopathological analysis revealed the surprising diagnosis of intraosseous schwannoma. Spinal Intraosseous Schwannomas (SIS) are rare benign tumors, often mimicking more sinister processes on diagnostic imaging. Fortunately, their histologic appearance is identical to schwannomas found more commonly in the soft tissues, providing diagnostic certainty to otherwise ambiguous radiologic findings. Though rare, intraosseous schwannomas remain an important benign diagnostic consideration for incidental solitary lytic bone lesions. To our knowledge, this is the second published case of kyphoplasty involving an SIS.

## Full-text entities

- **Diseases:** neck pain (MESH:D019547), trauma (MESH:D014947), fracture (MESH:D050723), pneumothorax (MESH:D011030), extramedullary tumors (MESH:D023981), bone erosion (MESH:D014077), Hyperthermia (MESH:D005334), numbness (MESH:D006987), bone tumor (MESH:D001859), chordoma (MESH:D002817), sensory deficit (MESH:D012678), Extraosseous tumor (MESH:D009369), vertebral body tumor (MESH:D002345), heart failure (MESH:D006333), bone lesion (MESH:D001847), peripheral sclerosis (MESH:D010523), anterior cortical destruction (MESH:D008105), pain (MESH:D010146), pathologic fracture (MESH:D005598), spindle cell neoplasm (MESH:D002277), diabetic neuropathy (MESH:D003929), dehiscence (MESH:D013529), emphysema (MESH:D004646), spinal hemangiomas (MESH:D006391), Multiple myeloma lesions (MESH:D009101), Intraosseous Schwannoma (MESH:D009442), myelopathy (MESH:D013118), muscle weakness (MESH:D018908), lesion (MESH:D009059), chondrosarcoma (MESH:D002813), bone plasmacytomas (MESH:D010954), spinal neoplasm (MESH:D013125), monoclonal gammopathy (MESH:D010265), C2 (OMIM:217000), benign nerve sheath tumors (MESH:D018317), vertebral body collapse (MESH:D001261), oncologic (MESH:D000072716), anterior extraosseous disease (MESH:D010900)
- **Chemicals:** PMMA (MESH:D019904), Tau (MESH:C000609666), lidocaine (MESH:D008012), H&amp;E (MESH:D006371)
- **Species:** Homo sapiens (human, species) [taxon 9606]
- **Mutations:** A 13G

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12077964/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12077964/full.md

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Source: https://tomesphere.com/paper/PMC12077964