# A Case of Coronary Sinus Atrial Septal Defect With Left Ventricular Thrombosis Treated With Minimally Invasive Cardiac Surgery

**Authors:** Yoshun Sai, Keita Kikuchi, Joji Ito

PMC · DOI: 10.7759/cureus.82260 · Cureus · 2025-04-14

## TL;DR

A rare heart defect combined with a blood clot in the left ventricle was successfully treated using minimally invasive surgery.

## Contribution

This is the first reported case of coronary sinus atrial septal defect with left ventricular thrombosis treated via minimally invasive surgery.

## Key findings

- Minimally invasive endoscopic surgery allowed successful repair of a coronary sinus atrial septal defect and removal of a left ventricular thrombus.
- The approach provided good exposure while preserving the sternum and enabling faster recovery.
- Percutaneous closure was not feasible due to anatomical limitations.

## Abstract

Coronary sinus atrial septal defect (CS‑ASD) is an uncommon congenital anomaly that accounts for <1% of all atrial septal defects. Over the past decade, around 10 adult CS‑ASD cases have been reported, and none have included simultaneous left ventricular (LV) thrombectomy.

We describe the case of a 71‑year‑old man who presented with chest pain and ST‑segment‑elevation myocardial infarction caused by proximal right coronary artery occlusion, which was successfully treated with stent placement. Subsequent cardiac examination revealed CS-ASD and LV thrombosis. Using an endoscopic approach, we successfully repaired the defect and removed the thrombus.

Because the defect lacked an adequate surrounding rim and a transcatheter device could jeopardize coronary‑sinus patency, percutaneous closure was deemed contraindicated, and thus surgical patch repair was undertaken. Endoscopic surgery performed via a right mini‑thoracotomy afforded excellent exposure of the atrial septum and LV cavity while being less invasive and allowing sternal preservation, thereby facilitating an expedited postoperative recovery, advantages that are particularly pertinent when concomitant CS‑ASD closure and LV thrombectomy are required.

## Linked entities

- **Diseases:** myocardial infarction (MONDO:0005068), atrial septal defect (MONDO:0006664)

## Full-text entities

- **Diseases:** coronary artery occlusion (MESH:D054059), edema (MESH:D004487), dyspnea (MESH:D004417), bleeding (MESH:D006470), ASDs (MESH:D006344), stenosis (MESH:D003251), ischemic stroke (MESH:D002544), ST-elevation myocardial infarction (MESH:D000072657), LV thrombus (MESH:D013927), embolic (MESH:D004617), septal defect (MESH:D006343), heart murmur (MESH:D006337), atrioventricular septal defects (MESH:C562831), paradoxical embolism (MESH:D019320), CS (MESH:D003323), tricuspid regurgitation (MESH:D014262), chest pain (MESH:D002637), renal or splenic infarction (MESH:D013159), ASD (MESH:D001321), myocardial infarction (MESH:D009203), infections (MESH:D007239), LV (MESH:D018487), MICS (MESH:D006331), congenital anomaly (MESH:D000013), CS syndrome (MESH:D054058), acute limb ischemia (MESH:D000208), PLSVC (MESH:D000083402), arrhythmias (MESH:D001145)
- **Chemicals:** Gore (-), Warfarin (MESH:D014859)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12077925/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12077925/full.md

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Source: https://tomesphere.com/paper/PMC12077925