# Liver Abscesses in Patients With Beta Thalassaemia Major: A Case Series and Mini-Review of the Literature

## TL;DR

This paper presents three cases of liver abscesses in patients with beta thalassaemia major and suggests treatment and monitoring strategies to manage this challenging condition.

## Contribution

The paper provides a case series and recommendations for managing liver abscesses in transfusion-dependent thalassaemia patients.

## Key findings

- Three transfusion-dependent thalassaemia patients experienced liver abscesses, with two having repeated episodes.
- Prolonged antibiotic treatment and regular imaging are recommended for managing and monitoring the condition.
- Maintaining continuous venous access is highlighted as a critical but often overlooked challenge.

## Abstract

Treatment of liver abscesses in patients with transfusion-dependent thalassaemia remains a challenging task due to the interplay of multiple factors, including difficult venous access and the co-existence of other organ dysfunction, such as diabetes mellitus. We report case histories of three transfusion-dependent thalassaemia patients with liver abscesses, two of whom had repeated episodes of the disease. We recommend a prolonged regimen of intravenous and oral antibiotics to eliminate the infection, along with more vigilant and regular follow-up using imaging for early detection of recurrence. Finally, we highlight the importance of maintaining continuous venous access - another often overlooked challenge among thalassaemia patients.