# Patient-specific guided Deep Circumflex Iliac Artery free flap for mandibular reconstruction in an ameloblastoma case. Case report and insights on the current state of customized surgery in H&N reconstruction in China

**Authors:** Íñigo Aragón Niño, Chongyang Zheng, Han Cheng, Yongjie Hu, Yue He

PMC · DOI: 10.4317/jced.62693 · Journal of Clinical and Experimental Dentistry · 2025-04-01

## TL;DR

A patient with recurring mandibular ameloblastoma was successfully treated using a customized deep circumflex iliac artery flap in China, highlighting the potential and challenges of personalized surgical approaches.

## Contribution

The paper presents a novel application of patient-specific guided surgery for mandibular reconstruction in a complex ameloblastoma case in China.

## Key findings

- Customized surgical planning improved precision in tumor resection and bone flap design.
- Patient-specific guides and pre-bent titanium plates enhanced functional and aesthetic outcomes.
- Regulatory and financial barriers hinder the widespread adoption of customized surgery in China.

## Abstract

This article presents a case of recurrent mandibular ameloblastoma treated with customized reconstructive surgery using a microvascularized DCIA bone flap. Virtual surgical planning and customized surgery, which has become increasingly adopted in head and neck reconstruction, enhances precision in tumor resection, flap design, and fixation, leading to superior functional and aesthetic outcomes.
The patient, initially treated with curettage in China (2017) and Japan (2021), presented with recurrence upon relocating to Shanghai. Imaging confirmed the diagnosis, and customized surgery was planned due to the complexity of the case. The surgical approach involved patient-specific cutting guides for both the mandibular resection and iliac crest flap harvesting, ensuring precise bone segmentation and reconstruction. Contouring guides were used to optimize bone alignment, and a pre-bent titanium reconstruction plate was employed. 
Despite the advantages of customized surgery, its widespread implementation in China faces regulatory and financial challenges. Restrictions on patient-specific implants and high costs limit accessibility, but alternative techniques, such as contouring guides, help improve outcomes. As regulations evolve and technology advances, customized surgery is expected to become a standard approach, improving reconstructive care in complex cases.

Key words:Mandibular ameloblastoma, guided surgery, customized reconstruction, head and neck, surgery in China.

## Linked entities

- **Diseases:** ameloblastoma (MONDO:0017795)

## Full-text entities

- **Diseases:** ameloblastoma (MESH:D000564), Mandibular ameloblastoma (MESH:D008338), H&amp;N (MESH:D000848), tumor (MESH:D009369)
- **Chemicals:** titanium (MESH:D014025)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12077833/full.md

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Source: https://tomesphere.com/paper/PMC12077833