# First Reported Use of Diluted HArmonyCa™ for Neck Rejuvenation: A Report of Two Cases

## TL;DR

This paper reports two cases where diluted HArmonyCa™ was used for neck rejuvenation and showed improvement without adverse effects.

## Contribution

The first reported use of diluted HArmonyCa™ for neck rejuvenation with documented results using validated scales.

## Key findings

- Both patients showed a one-point improvement in GAIS scores.
- Neck line severity improved from moderate to mild and severe to mild on the ATNL scale.
- No adverse events were observed with the diluted HArmonyCa™ treatment.

## Abstract

Neck rejuvenation is one of the most commonly sought-after treatments in aesthetic medicine. This study demonstrates neck rejuvenation using dilute HArmonyCa™. To date, there have been no publications regarding the efficacy of HArmonyCa™ in the neck. Two female patients who presented for neck rejuvenation were injected using dilute HArmonyCa™. The product was diluted using a ratio of 1:1, using normal saline. The patients and the injecting doctor completed the Global Aesthetic Improvement Scale (GAIS) to assess the results. The Allergan Transverse Neck Lines (ATNL) scale was also used to rate the severity of neck lines, and a one-point improvement was used as a marker of a successful treatment. The mean age of the patients was 55 years. Both patients achieved a one-point improvement in the GAIS score. Prior to treatment, Patient 1 was rated “moderate” (2 out of 4) on the ATNL. Patient 2 was rated “severe” (4 out of 4). Post-treatment, both patients dropped down to 1. No adverse events were noted. Dilute HArmonyCa™ was well tolerated in the neck. The patients achieved improvement in their neck lines, with a one-point improvement using validated scales. This case series paves the way for a larger study, with a longer follow-up.