# Atypical Radiological Presentation of a Neonatal Primary Retroperitoneal Teratoma Undergoing Haemorrhagic Evolution: A Case Report

**Authors:** Sana Shah Alam, Jeevika Ujjappa

PMC · DOI: 10.7759/cureus.82217 · Cureus · 2025-04-13

## TL;DR

A rare case of a neonate with a primary retroperitoneal teratoma that showed unusual radiological signs and led to abdominal complications is reported.

## Contribution

This case report highlights the atypical radiological presentation of a neonatal retroperitoneal teratoma undergoing haemorrhagic evolution.

## Key findings

- The neonate's prenatal imaging showed a cystic lesion that later developed solid components and calcifications.
- Surgical excision and histopathological analysis confirmed a haemorrhagic infarction of a teratoma.
- The case emphasizes the need for early detection and multidisciplinary management for optimal outcomes.

## Abstract

Primary retroperitoneal teratomas are rare extragonadal germ cell tumours that originate from totipotent embryonic cells misplaced during embryogenesis. These tumors are more commonly seen in neonates and infants and may remain asymptomatic until they reach a significant size, leading to compressive symptoms. Here, we present a case of a 15-day-old neonate with progressive abdominal distension since birth and a fever for three days. Prenatal ultrasonographic imaging at 22-23 weeks gestation detected an intra-abdominal cystic lesion, initially suspected to be a duplication or mesenteric cyst. By 29-30 weeks, the lesion showed solid components with possible calcifications, raising suspicion of an intra-abdominal teratoma. Through detailed clinical evaluation, radiographic imaging, and diagnostic modalities, including chest radiography, ultrasound, computed tomography and magnetic resonance imaging, the anatomical features and associated complications were delineated. Surgical excision was performed, and histopathological examination revealed haemorrhagic infarction of a teratoma, confirming the diagnosis. Primary retroperitoneal teratomas in neonates are uncommon and may mimic other congenital cystic or solid abdominal masses. This case underscores the importance of early detection and multidisciplinary management in optimizing outcomes.

## Linked entities

- **Diseases:** teratoma (MONDO:0002601)

## Full-text entities

- **Genes:** AFP (alpha fetoprotein) [NCBI Gene 174] {aka AFPD, FETA, HPAFP}
- **Diseases:** intra-abdominal cystic lesion (MESH:C535553), calcification (MESH:D002114), abdominal distension (MESH:D000007), mesenteric cyst (MESH:D008639), Wilms tumor (MESH:D009396), compressive (MESH:D009408), adipose tissue (MESH:D018205), liposarcoma (MESH:D008080), duplication (MESH:D058674), haemorrhage (MESH:D006470), intra-abdominal cyst (MESH:D000082122), ascites (MESH:D001201), congenital cysts of the pancreas (MESH:D003560), Retroperitoneal germ cell tumors (MESH:D009373), retroperitoneal tumor (MESH:D012186), tenderness (MESH:D063806), anaemia (MESH:D000743), lymphangiomas (MESH:D008202), vomiting (MESH:D014839), fever (MESH:D005334), Neuroblastomas (MESH:D009447), necrosis (MESH:D009336), pancreatoblastomas (MESH:C537162), back or abdominal pain (MESH:D015746), bone masses (MESH:D001847), cystic (MESH:D018297), myelolipoma (MESH:D018209), congenital tumours (MESH:D009369), cystic lesion (MESH:D052177), pain (MESH:D010146), constipation (MESH:D003248), intra (MESH:D057072), nausea (MESH:D009325), Primary retroperitoneal teratomas (MESH:D013724)
- **Chemicals:** hematoxylin (MESH:D006416), H%E (-), eosin (MESH:D004801)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

9 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12076036/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12076036/full.md

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Source: https://tomesphere.com/paper/PMC12076036