# Editorial: Integrative pharmacological approaches for regenerating cartilage and bone tissue

**Authors:** Jiahui Tan, Jie Fang, Wen Liao, Lufei Wang

PMC · DOI: 10.3389/fphar.2025.1613512 · Frontiers in Pharmacology · 2025-04-30

## Full-text entities

- **Genes:** Ccn2 (cellular communication network factor 2) [NCBI Gene 14219] {aka Ctgf, Fisp12, Hcs24, fisp-12}, Yap1 (yes-associated protein 1) [NCBI Gene 22601] {aka Yap, Yap65, Yki, Yorkie}
- **Diseases:** pain (MESH:D010146), osteonecrosis of the femoral head (MESH:D000070603), inflammation (MESH:D007249), bone defects (MESH:D001847), fractures (MESH:D050723), diabetic (MESH:D003920), knee OA (MESH:D020370), destruction of cartilage and bone tissue (MESH:D018213), osteoporosis (MESH:D010024), OA (MESH:D010003)
- **Chemicals:** poly (lactic-co-glycolic acid) (MESH:D000077182), metformin (MESH:D008687), hydroxyapatite (MESH:D017886), metal-organic frameworks (MESH:D000073396), TXA (MESH:D014148), pamrevlumab (MESH:C560078), monosodium iodoacetate (MESH:D019807), HA (MESH:D006820)
- **Species:** Mus musculus (house mouse, species) [taxon 10090], Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12075252/full.md

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Source: https://tomesphere.com/paper/PMC12075252