# Ultrasonographic findings in mid-trimester adolescent pregnancy: prevalence and risk of abnormalities

**Authors:** Jakub Staniczek, Maisa Manasar-Dyrbuś, Rafał Stojko, Patrycja Sodowska, Magda Rybak-Krzyszkowska, Adrianna Kondracka, Marcin Sadłocha, Krzysztof Sodowski, Agata Włoch, Bartosz Czuba, Wojciech Cnota, Miriam Illa, Agnieszka Drosdzol-Cop

PMC · DOI: 10.3389/fmed.2025.1525149 · Frontiers in Medicine · 2025-04-30

## TL;DR

Adolescent pregnancies show higher fetal abnormalities in mid-trimester ultrasounds compared to older women.

## Contribution

The study reveals that adolescent pregnancies are not protected from fetal abnormalities and require high-risk classification.

## Key findings

- Adolescent pregnancies had a higher prevalence of fetal abnormalities (437.075 per 1,000 pregnancies).
- Abnormalities in brain, spine, face, heart, and urinary tract were notably higher in adolescents.
- Ultrasound screening is essential for adolescent pregnancies due to increased risk of fetal abnormalities.

## Abstract

Adolescent pregnancy, defined as pregnancy in females aged 19 or younger, is associated with higher risks for adverse outcomes compared to older women. Ultrasound imaging during the mid-trimester is crucial for prenatal care, providing insights into fetal development and maternal health.

The primary aim of this study is to evaluate and compare mid-trimester ultrasound findings between adolescent and older pregnant women and to assess the prevalence and risk of any abnormalities detected during ultrasound examinations.

This retrospective study was conducted in the Silesian Voivodeship, Poland, from January 1, 2004, to February 29, 2024. Data were collected from reference prenatal centers. The study included 37,366 individuals, of which 1,152 were adolescents. Participants underwent second-trimester prenatal screening, and ultrasound findings were categorized into fetal abnormalities and maternal factors.

The study found significant differences in ultrasonographic findings across different age groups. Adolescent pregnancies showed a higher prevalence of fetal abnormalities, 437.075 per 1,000 pregnancies (95% CI: 409–465). Brain, spine, facial, heart, and urinary tract abnormalities were notably higher in group adolescents.

Adolescent pregnancies are associated with increased detection of various fetal abnormalities during mid-trimester ultrasound scans. Contrary to common belief, the young age of adolescent pregnant individuals does not protect against fetal abnormalities. These findings underscore the necessity for comprehensive, population-based ultrasound screening for pregnant adolescents and the classification and management of adolescent pregnancies as high-risk.

## Full-text entities

- **Diseases:** hypertelorism (MESH:D006972), Arteries (MESH:D012078), gastrointestinal tract abnormalities (MESH:D005770), anemia (MESH:D000740), Fetal abnormalities (MESH:D005315), Limb deficiencies (MESH:D001259), Gastroschisis (MESH:D020139), nuchal edema (MESH:D004487), Congenital pulmonary airway malformation (MESH:D056151), Pleural effusion (MESH:D010996), facial defects (MESH:D005153), clubfoot (MESH:D003025), ascites (MESH:D001201), Blake's pouch cyst (MESH:D003560), agenesis of the inferior vena cava (MESH:C563013), autosomal dominant polycystic kidney disease (MESH:D016891), Cystic hygroma (MESH:D018191), Abnormalities (MESH:D000014), ductus venosus (MESH:C562830), NCA (MESH:D002869), Microcephaly (MESH:D008831), PA (MESH:D018633), FAS (MESH:D063647), oligodactyly (MESH:C535688), female genital defects (MESH:D005831), Corpus callosum agenesis (MESH:D061085), undescended testes (MESH:D003456), Radius agenesis (MESH:D011885), hypospadias (MESH:D007021), Bladder exstrophy (MESH:D001746), HRHS (MESH:C537795), obstructive (MESH:D000402), esophageal atresia (MESH:D004933), AVSD (MESH:C562831), Megacystis (MESH:C536139), humeral agenesis (MESH:D006810), central nervous, gastrointestinal, and musculoskeletal anomalies (MESH:D009139), thoracic abnormality (MESH:D013896), lower limb abnormalities (MESH:D038061), amniotic (MESH:D000652), Choroid plexus cysts (MESH:D020288), Amniotic fluid abnormalities (MESH:D004619), Autosomal recessive polycystic kidney disease (MESH:D017044), Cerebellar hypoplasia (MESH:C562568), Cervical teratoma (MESH:D013724), TAC (MESH:D014339), Hypertrophic cardiomyopathy (MESH:D002312), Brain abnormalities (MESH:D001927), genetic disorders (MESH:D030342), Aortic Coarctation (MESH:D001017), HLHS (MESH:D018636), Tachycardia (MESH:D013610), VSD (MESH:D006345), hypoplastic aortic arch (MESH:D001015), Ventriculomegaly (MESH:D006849), mega cisterna magna (MESH:D000070603), Holoprosencephaly (MESH:D016142), ectrodactyly (MESH:C574275), urinary system defects (MESH:D015619), congenital heart defects (MESH:D006330)
- **Chemicals:** vitamin B12 (MESH:D014805), alcohol (MESH:D000438), folate (MESH:D005492), iron (MESH:D007501)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

32 references — full list in the complete paper: https://tomesphere.com/paper/PMC12074930/full.md

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Source: https://tomesphere.com/paper/PMC12074930