# An Examination of the Effect of Parent‐Centered Nutrition Education on the Oxidant‐Antioxidant Parameters of Children Diagnosed With Autism Spectrum Disorder

**Authors:** Diler Us Altay, Erman Esnafoglu, Emine Kocyigit, Duygu Mataraci Değirmenci, Tevfik Noyan

PMC · DOI: 10.1002/brb3.70504 · Brain and Behavior · 2025-05-13

## TL;DR

This study found that nutrition education for families of children with autism improved eating habits and dietary patterns, even without significant changes in oxidative stress markers.

## Contribution

The study demonstrates that parent-centered nutrition education can improve dietary behaviors in children with autism, despite no significant impact on antioxidant levels.

## Key findings

- Nutrition education led to improved eating behaviors and dietary patterns in children with autism.
- There was no significant change in oxidant-antioxidant parameters between groups.
- BAMBI scores decreased significantly in the experimental group after the intervention.

## Abstract

This study examined the effect of nutrition education given by dietitians to families of children aged 3–18 diagnosed with autism spectrum disorder (ASD) on meal consumption, eating behaviors, autism severity, serum oxidant/antioxidant marker levels, and total dietary antioxidant capacity.

The project was carried out with 44 pediatric patients diagnosed with ASD and their parents. The ELISA method was used for antioxidant and oxidant measurements, and the oxygen radical absorbance capacity values ​​of foods defined according to the BeBiS program were used to calculate the total dietary antioxidant capacity. The children's eating behavior questionnaire, childhood autism rating scale (CARS), and brief autism mealtime behavior inventory (BAMBI) were administered.

There was no significant difference in antioxidant and oxidant parameters between the experimental and control groups. At the end of eight weeks, superoxide dismutase and glutathione levels increased significantly in the experimental group. There was no significant difference in terms of the families of the autistic children in the experimental and control groups or their disease‐specific knowledge. BAMBI scores were similar between the groups at baseline, while a significant decrease was observed in the experimental group at the end of the study. Daily energy, saturated fatty acid (SFA), carbohydrate, and omega‐6 intake decreased, while protein, fat, mono‐ and poly‐unsaturated fatty acid, and omega‐3 intake increased in the experimental group following nutrition education. However, these results were not statistically significant. There was no significant difference in terms of micronutrient intake between children with ASD in experimental and control groups before and after nutrition education.

Improvements in eating habits and dietary patterns were noted after nutrition education, especially in the experimental group, even though there were no appreciable changes in oxidative stress indicators. These behavioral shifts imply that family nutrition education can be extremely important in encouraging better eating practices and improving the general well‐being of kids with ASD and their families.

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that produces symptoms from the early years of life. This study was conducted to examine the effect on total antioxidant capacity and antioxidant–oxidant parameters in the diet in children of nutrition education provided by specialist dieticians for the families of children diagnosed with ASD aged 3–18 years. As a result, it shows that the nutrition education provided helps children with ASD acquire healthy nutrition and eating habits, prevents nutritional deficiencies, alleviates nutrition‐related symptoms, ensures healthy growth and development, improves the quality of life of families, and reduces stress factors.

## Linked entities

- **Diseases:** autism spectrum disorder (MONDO:0005258)

## Full-text entities

- **Diseases:** ASD (MESH:D000067877), autism (MESH:D001321)
- **Chemicals:** carbohydrate (MESH:D002241), mono- and poly-unsaturated fatty acid (-), oxygen (MESH:D010100), SFA (MESH:D005227), glutathione (MESH:D005978)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

58 references — full list in the complete paper: https://tomesphere.com/paper/PMC12074868/full.md

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Source: https://tomesphere.com/paper/PMC12074868