# Comparing Early Outcomes and Complications Between Total Ankle Arthroplasty and Ankle Arthrodesis in Patients with Ankle Osteoarthritis: Big Data Analysis

**Authors:** Assil Mahamid, Lior Laver, David Maman, Amir Abu Elhija, Mohammad Haj Yahya, Daniel Haverkamp, Yaron Berkovich, Eyal Behrbalk

PMC · DOI: 10.3390/jcm14092909 · Journal of Clinical Medicine · 2025-04-23

## TL;DR

This study compares the outcomes of two surgical treatments for severe ankle arthritis using national data to help guide patient care decisions.

## Contribution

The study provides new insights into the trends and early outcomes of total ankle arthroplasty versus ankle arthrodesis using a large national dataset.

## Key findings

- Total ankle arthroplasty (TAA) usage increased while ankle arthrodesis (AA) decreased between 2016 and 2019.
- TAA patients were older and had fewer comorbidities compared to AA patients.
- TAA was associated with lower immediate risks and is increasingly preferred for end-stage ankle osteoarthritis.

## Abstract

Background: End-stage ankle osteoarthritis (OA) severely limits function and quality of life. Total ankle arthroplasty (TAA) and ankle arthrodesis (AA) are key surgical interventions when conservative treatment fails. This study compares TAA and AA outcomes using a national dataset to inform patient-centered care. Methods: A retrospective analysis of 27,595 patients undergoing TAA or AA from 2016–2019 was conducted using the National Inpatient Sample. Propensity score matching addressed baseline differences. Results: Primary OA was more prevalent in TAA (85.9%) than in AA (55.4%). TAA utilization rose from 73% to 78% (p < 0.0001), while AA declined. TAA patients were older (65.6 vs. 59.7 years), more often Medicare-insured, and predominantly Caucasian. AA patients had higher rates of comorbidities, including diabetes, obesity, lung disease, and mental disorders (all p < 0.0001). Conclusions: TAA and AA cater to distinct patient profiles. TAA is increasingly favored and associated with lower immediate risks, though procedure choice should be individualized based on comorbidities and risk profiles. These insights support evidence-based decision-making in end-stage ankle OA management.

## Linked entities

- **Diseases:** osteoarthritis (MONDO:0005178), diabetes (MONDO:0005015), obesity (MONDO:0011122), lung disease (MONDO:0005275)

## Full-text entities

- **Diseases:** mental disorders (MESH:D001523), diabetes (MESH:D003920), Complications (MESH:D008107), Ankle Osteoarthritis (MESH:D016512), obesity (MESH:D009765), OA (MESH:D010003), lung disease (MESH:D008171)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12072959/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12072959/full.md

## References

42 references — full list in the complete paper: https://tomesphere.com/paper/PMC12072959/full.md

---
Source: https://tomesphere.com/paper/PMC12072959