# 18F-FDG PET/CT Findings in Glandular Tularemia

**Authors:** Freja Gustafsson, Karl Keigo Rasmussen, Kristina Thorsteinsson, Anne-Mette Lebech, Lasse Fjordside

PMC · DOI: 10.3390/diagnostics15091159 · 2025-05-02

## TL;DR

A woman with glandular tularemia showed high metabolic activity on a PET/CT scan, highlighting the challenges in diagnosing this disease.

## Contribution

This case illustrates the role of 18F-FDG PET/CT in diagnosing glandular tularemia when other methods are inconclusive.

## Key findings

- PET/CT showed high metabolic activity in the left inguinal region, suggesting abscesses.
- Diagnosis was confirmed with PCR and serology for Francisella tularensis.
- The case emphasizes the difficulty in diagnosing tularemia and the value of imaging.

## Abstract

A 47-year-old woman presented with fever, fatigue, night sweats and inguinal glandular swelling following a tick bite. Weeks of diagnostic uncertainty followed, and a lymph node biopsy was sent to be investigated for tularemia and pathology. An 18F-FDG PET/CT scan was performed due to a suspicion of malignant lymphoma. The scan revealed high metabolic activity in the left inguinal region, which was compatible with abscesses. The diagnosis of glandular tularemia was established on a positive PCR for Francisella tularensis (F. tularensis) and positive F. tularensis serology. This case highlights the challenges of diagnosing tularemia and illustrates the role of imaging.

## Linked entities

- **Chemicals:** 18F-FDG (PubChem CID 68614)
- **Diseases:** tularemia (MONDO:0018077), malignant lymphoma (MONDO:0005062)
- **Species:** Francisella tularensis (taxon 263)

## Full-text entities

- **Diseases:** fatigue (MESH:D005221), fever (MESH:D005334), Glandular Tularemia (MESH:D014406), malignant lymphoma (MESH:D008223), tick bite (MESH:D064927), swelling (MESH:D004487), abscesses (MESH:D000038)
- **Species:** Francisella tularensis (species) [taxon 263], Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12071816/full.md

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Source: https://tomesphere.com/paper/PMC12071816