# Arrhythmic Risk Stratification in Patients with Arrhythmogenic Cardiomyopathy

**Authors:** Marisa Varrenti, Eleonora Bonvicini, Leandro Fabrizio Milillo, Ilaria Garofani, Marco Carbonaro, Matteo Baroni, Lorenzo Gigli, Giulia Colombo, Federica Giordano, Raffaele Falco, Antonio Frontera, Roberto Menè, Alberto Preda, Sara Vargiu, Patrizio Mazzone, Fabrizio Guarracini

PMC · DOI: 10.3390/diagnostics15091149 · Diagnostics · 2025-04-30

## TL;DR

This paper reviews current methods for predicting arrhythmia risk in patients with a heart disease that causes sudden cardiac death.

## Contribution

The paper provides a comprehensive review of recent studies and developments in arrhythmic risk stratification for arrhythmogenic cardiomyopathy.

## Key findings

- Arrhythmogenic cardiomyopathy leads to sudden cardiac death, often without prior symptoms.
- Stratifying arrhythmic risk remains a challenge for clinicians managing these patients.
- The paper highlights new developments and important studies in risk stratification methods.

## Abstract

Arrhythmogenic cardiomyopathy is a heart disease in which the heart muscle is replaced by scar tissue. This is the main substrate for the development of malignant ventricular arrhythmias. Sudden cardiac death is the most common manifestation and can often be the first sign of the disease, especially in young people. Correct stratification of arrhythmic risk is essential for the management of these patients but remains a challenge for the clinical cardiologist. In this context, the aim of our work was to review the literature and to analyse the most important studies and new developments with regard to the stratification of the risk of arrhythmia in patients suffering from arrhythmogenic cardiopathy.

## Linked entities

- **Diseases:** sudden cardiac death (MONDO:0007264)

## Full-text entities

- **Diseases:** Arrhythmogenic Cardiomyopathy (MESH:D019571), Arrhythmic (OMIM:212500), heart disease (MESH:D006331), arrhythmogenic cardiopathy (MESH:C536187), arrhythmia (MESH:D001145), Sudden cardiac death (MESH:D016757)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12071219/full.md

## References

96 references — full list in the complete paper: https://tomesphere.com/paper/PMC12071219/full.md

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Source: https://tomesphere.com/paper/PMC12071219