This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction Note: Topical antibiotics reduce CD11c+ cell numbers in the healthy murine cornea and modulate their response to contact lens wear
Ananya Datta, Justin Lee, Tiffany Truong, David J. Evans, Suzanne M. J. Fleiszig
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsOcular Surface and Contact Lens · Corneal Surgery and Treatments · Corneal surgery and disorders
Retraction of: Scientific Reports 10.1038/s41598-022-14847-x, published online 23 June 2022
The Authors have retracted this Article. Following detection of duplicated images in two panels, the Authors carried out a broad investigation of the raw data contributing to all 10 panels in Figs. 2 and 3. The raw data consisted of confocal image Z-stacks through the entire thickness of the cornea of mouse eyes, each composed of many images. These were used to reconstruct corneal tissue regions in 3D, before the number of cells present was quantified using Imaris software (quantitative results shown in Figs. 2b and 3b). To produce the panels in Figs. 2a and 3a, Imaris software was used to collapse the image stacks, thereby allowing all cells in representative 3D tissue blocks to be viewed in 2D. Thus, the images shown in the panels were not individual captured images, and the cells shown in each were not necessarily all in the same plane. After reviewing the original files stored on the confocal microscope used to capture the images, the Authors found unexplained inconsistencies in file labeling that have undermined their confidence in the conclusions of the paper.
Ananya Datta and Suzanne M. J. Fleiszig agree to retract this article. Justin Lee, Tiffany Truong and David J. Evans did not respond to correspondence from the publisher regarding the retraction.