# Masquelet technique combined with a lantern-mimicking frame system for treatment of a 28-cm infected bone defect: a case report

**Authors:** Ji Qv, Feng Gu, Yanbing Wang, Chuangang Peng, Dankai Wu

PMC · DOI: 10.3389/fsurg.2025.1577774 · Frontiers in Surgery · 2025-04-29

## TL;DR

A 55-year-old man with a 28-cm infected bone defect was successfully treated using the Masquelet technique combined with a Lantern-Mimicking Frame System.

## Contribution

This is the first reported case of successful treatment of a ≥28 cm infected bone defect using the Masquelet technique.

## Key findings

- The patient could walk normally without crutches 14 months after surgery.
- The treatment achieved favorable clinical results without pain in daily life.
- The length of the defect was not an absolute limiting factor for the Masquelet technique.

## Abstract

Treatment of large bone defects resulting from acute injury or infection remains challenging. The Masquelet technique is a two-stage procedure for treating bone defects caused by bone tumor resection, infection, or trauma. There are currently no reports of successful repair of ≥28 cm bone defects using the Masquelet technique.

We describe the case of a 55-year-old man with postoperative infection of a femoral fracture and a 28-cm infected bone defect formed after multiple debridement procedures. The Masquelet technique, when coupled with a Lantern-Mimicking Frame System (LMFS), achieved favorable clinical results. The patient could walk normally without crutches 14 months postoperatively and did not experience pain in daily life.

This was the longest bone defect in a single limb currently reported to had been cured in the literature. The Masquelet technique coupled with LMFS achieved favorable clinical results for the treatment of a 28-cm infected bone defect. For extremely large bone defects in a single limb, the length of the defect was not an absolute limiting condition for the indications of Masquelet technique.

## Linked entities

- **Diseases:** infection (MONDO:0005550)

## Full-text entities

- **Diseases:** femoral fracture (MESH:D005264), pain (MESH:D010146), infection (MESH:D007239), bone tumor (MESH:D001859), bone defect (MESH:D001847), injury (MESH:D014947)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12069447/full.md

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12069447/full.md

## References

34 references — full list in the complete paper: https://tomesphere.com/paper/PMC12069447/full.md

---
Source: https://tomesphere.com/paper/PMC12069447