# Auditory Brainstem Response Findings in Children with Level 1 Autism Spectrum Disorder: A Comparative Study

**Authors:** Mariana de Medeiros Cardoso, Rudimar dos Santos Riesgo, Pricila Sleifer

PMC · DOI: 10.1055/s-0044-1792084 · International Archives of Otorhinolaryngology · 2025-05-12

## TL;DR

This study compares auditory brainstem responses in children with autism and typically developing children, finding delays in signal processing in those with autism.

## Contribution

The study identifies specific auditory pathway impairments in children with autism spectrum disorder through brainstem response measurements.

## Key findings

- Children with autism had significantly longer latencies for waves III and V in auditory brainstem responses.
- Increased interpeak intervals III to V and I to V were observed in children with autism compared to controls.

## Abstract

Introduction
 Autism spectrum disorder is a pervasive developmental disorder characterized by deficits in communication and social interactions, as well as repetitive behavioral patterns. Understanding the relationship between auditory brainstem response and hearing is crucial, considering the importance of sensory function. Auditory brainstem response testing is a tool that evaluates the auditory system from periphery to brainstem in response to an acoustic stimulus, providing important information about the auditory pathways.

Objective
 To compare auditory brainstem response findings in children with autism spectrum disorder versus those of a control group.

Methods
 Cross-sectional, comparative study of 23 children (age 7–10 years) diagnosed with autism spectrum disorder and an age- and sex-matched control group of normal-hearing children with typical development. All participants underwent otoscopy, impedance audiometry, pure-tone audiometry, speech audiometry, and brainstem evoked response audiometry.

Results
 Statistically significant between-group differences were seen on comparison of the absolute latencies of waves III (
p
 = 0.047) and V (
p
 = 0.034), as well as interpeak intervals III to V (
p
 = 0.048) and I to V (
p
 = 0.036), with increased values in the study group. The sample was composed of 8.7% females and 91.3% males.

Conclusion
 In this sample, children with autism spectrum disorder showed increased auditory brainstem response latencies compared to the control group, suggesting auditory pathway impairment.

## Linked entities

- **Diseases:** autism spectrum disorder (MONDO:0005258)

## Full-text entities

- **Diseases:** pathway (MESH:D058606), Autism Spectrum Disorder (MESH:D000067877), pervasive developmental disorder (MESH:D002659)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12068944/full.md

## References

64 references — full list in the complete paper: https://tomesphere.com/paper/PMC12068944/full.md

---
Source: https://tomesphere.com/paper/PMC12068944