# The impact of a disparity-reduction intervention on outcomes of patients with acute coronary syndrome in the emergency department: a clinical trial

**Authors:** Mehdi Moradinia, Sajad Yarahmadi, Mehdi Birjandi, Mohammad Gholami

PMC · DOI: 10.1186/s12939-025-02496-1 · International Journal for Equity in Health · 2025-05-12

## TL;DR

This study tested an intervention to reduce disparities in emergency care for acute coronary syndrome patients, finding it improved pain management and long-term outcomes.

## Contribution

A disparity-reduction intervention combining improved triage and patient navigation was evaluated in an ED setting for ACS patients.

## Key findings

- The intervention significantly reduced pain intensity and threat perception in patients.
- Patient opinion of pain management and illness perception improved more in the intervention group.
- Long-term outcomes like specialist visits and readmissions were better in the intervention group.

## Abstract

Patients with acute coronary syndrome (ACS) who belong to marginalized groups often do not receive equitable treatment and care when they are referred to emergency departments (ED), and this can have negative consequences for these patients. Therefore, this study aimed to evaluate the impact of a disparity-reduction intervention on outcomes of patients with ACS in the ED.

This randomized clinical trial included 264 ACS patients, randomly allocated into intervention (n = 132) and control group (n = 132). The intervention involved improving the triage process by (1) welcoming nurses and (2) conducting specialized triage. Also, a patient navigation (PN) program was implemented, comprising (1) emergency care comprehensive management, (2) supportive education and counseling, and (3) clinical actions with follow-up care. In the control group, standard triage and routine care were provided. Outcomes assessed included pain intensity, patient opinion of pain management, illness perception, threat perception, and short and long-term outcomes.

The results showed that after the intervention, pain intensity and threat perception decreased significantly in the intervention group compared to the control group (P < 0.001). Moreover, the opinion of pain management—assessed only post-intervention—was significantly more favorable in the intervention group than in the control group (P < 0.001). Illness perception scores also increased more prominently in the intervention group than in the control group (P < 0.001). Short-term outcomes showed improvement in the intervention group compared to the control group (P < 0.05). Long-term outcomes revealed that the intervention group experienced better results than the control group in specialist visits, exercise stress tests, echocardiography, and readmissions (P < 0.05).

Interventions such as improving the triage process and the PN are important in reducing disparities and improving patient outcomes. These findings underscore the effectiveness of tailored strategies in promoting equitable care in ED.

The online version contains supplementary material available at 10.1186/s12939-025-02496-1.

## Linked entities

- **Diseases:** acute coronary syndrome (MONDO:0005542)

## Full-text entities

- **Diseases:** ACS (MESH:D054058), pain (MESH:D010146)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

3 references — full list in the complete paper: https://tomesphere.com/paper/PMC12067677/full.md

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Source: https://tomesphere.com/paper/PMC12067677