# First person – Daniyal Jafree

## TL;DR

This paper discusses microvascular changes in a mouse model of polycystic kidney disease, as presented in an interview with the first author.

## Contribution

The paper highlights early microvascular aberrations in a Pkd1 mutant mouse model of polycystic kidney disease.

## Key findings

- Microvascular changes are an early feature in Pkd1 mutant mice.
- Findings align with observations in human polycystic kidneys.

## Abstract

First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping researchers promote themselves alongside their papers. Daniyal Jafree is first author on ‘
Microvascular aberrations found in human polycystic kidneys are an early feature in a Pkd1 mutant mouse model’, published in DMM. Daniyal is a postdoctoral clinical research fellow in the lab of Professor David Long at UCL Great Ormond Street Institute of Child Health, London, UK, investigating the formation and function of the vasculature during development, health and disease.