# Examining rural health equity and impact through the translational science benefits model: outcomes from the CTSA Consortium of Rural States (CORES)

**Authors:** Maggie Padek, Rebecca Butcher, Rebecca deLacerda Allen, Hilary L. Surratt, Maran Subramain, Beth Tigges, Alyson G. Eggleston, Jessica H. Presley, Trent Matheson, Nasser Sharareh

PMC · DOI: 10.3389/fpubh.2025.1538494 · Frontiers in Public Health · 2025-04-28

## TL;DR

This paper examines how rural health initiatives translate research into benefits using a model called TSBM, highlighting a focus on community and clinical impacts over economic and policy ones.

## Contribution

The paper introduces a novel application of the Translational Science Benefits Model to rural health research and evaluation.

## Key findings

- 184 rural-focused activities were identified across eight CTSA hubs from 2021–2023.
- All efforts had impacts in the Community and Clinical domains, with over 60% focused on Community impacts.
- There is an identified gap in measuring Economic and Policy-level impacts in rural health initiatives.

## Abstract

Rural communities often lack access to healthcare, have limited resources and infrastructure, and may experience suboptimal translation of evidence-based interventions into practice or measurement of translational research impact. The Consortium of Rural States (CORES), comprising eight Clinical and Translational Science Award (CTSA) hubs, is a research consortium that focuses on clinical and translational research impacting rural health.

Utilizing the Translational Science Benefits Model (TSBM) framework, each CTSA hub’s evaluation lead co-created an inventory of rural-focused activities, projects, and initiatives that occurred at their respective site during the funding period 2021–2023. Variables included program area; activity type and description; target population; activity status; outputs; and short-term outcomes. The evaluators then mapped site outcomes according to the four TSBM domains (clinical, community, economic, policy) and 30 subcategories (benefits).

184 rural-focused activities, projects and initiatives were identified across the hubs. All rural-focused efforts involved impacts in the Community and Clinical domains of the TSBM, with >60% focusing on Community impacts. These results suggest an opportunity gap to better define Economic and Policy-level impacts in the context of rural-focused initiatives.

This work demonstrates a novel mapping of the TSBM to rural health research settings and explores the nuances of using the concepts and domains of the TSBM as a coding tool. This work gives the Consortium insight on the types of projects and impacts that are supported and how to prioritize more exploration of the full range of translational science benefits in rural health initiatives going forward.

## Full-text entities

- **Genes:** CTSA (cathepsin A) [NCBI Gene 5476] {aka BSVD6, GLB2, GSL, NGBE, PPCA, PPGB}
- **Diseases:** opioid use disorders (MESH:D009293), chronic diseases (MESH:D002908), COVID-19 (MESH:D000086382), TSBM (MESH:D004195)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12066754/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12066754/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12066754/full.md

---
Source: https://tomesphere.com/paper/PMC12066754