# Incidental low-grade appendiceal mucinous neoplasm in Crohn’s disease patient post ileocecal resection: a case report

**Authors:** Mohammed Dakhel Aldakhil, Jawaher A Alowayyid, Mashel A Alzunidi, Raghad Ibrahim Albarrak

PMC · DOI: 10.1093/jscr/rjaf294 · Journal of Surgical Case Reports · 2025-05-12

## TL;DR

A rare case of a low-grade appendiceal tumor was found in a Crohn’s disease patient after surgery, highlighting the need for careful diagnosis in inflammatory bowel disease patients.

## Contribution

This paper presents a rare case of appendiceal mucinous neoplasm in a Crohn’s disease patient, emphasizing diagnostic challenges in IBD patients.

## Key findings

- Appendiceal mucinous neoplasm was diagnosed in a Crohn’s disease patient post ileocecal resection.
- The case highlights the importance of pathological evaluation in IBD patients with persistent symptoms.
- Such tumors are rare in IBD patients but require high suspicion for accurate diagnosis.

## Abstract

Appendiceal mucinous neoplasm is a rare tumor, found in 0.2%–0.3% of appendectomies. Inflammatory bowel disease (IBD) is a known risk factor for colorectal cancer; however, appendiceal mucinous neoplasm is rarely reported in IBD patients. Here we report a rare case in a patient with Crohn’s disease after ileocecal resection. She complained of recurrent, severe right lower quadrant pain. Further investigation revealed stenosis at the terminal ileum with a clear appendiceal orifice on magnetic resonance enterography and colonoscopy. She was referred for surgical evaluation after failure of medical management. The diagnosis of low-grade appendiceal mucinous neoplasm was confirmed by pathology after an uneventful laparoscopic ileocecal resection. Although this tumor is rare in IBD patients, a high index of suspicion is needed in those presenting with disease flare-ups, and pathological examination remains essential for diagnosis. This case underscores the diagnostic challenges and clearly highlights the importance of thorough evaluation.

## Linked entities

- **Diseases:** Crohn’s disease (MONDO:0005011), inflammatory bowel disease (MONDO:0005265), colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** stenosis (MESH:D003251), tumor (MESH:D009369), Appendiceal mucinous neoplasm (MESH:D001063), pain (MESH:D010146), IBD (MESH:D015212), Crohn's disease (MESH:D003424), colorectal cancer (MESH:D015179)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12066405/full.md

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12066405/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12066405/full.md

---
Source: https://tomesphere.com/paper/PMC12066405