# Nap duration and its association with hypertension-diabetes comorbidity in minority populations: evidence from the CMEC study

**Authors:** Renhua Zhang, Enhui Zhou, Leilei Liu, Yuan Wang, Fei Xiao, Feng Hong

PMC · DOI: 10.3389/fendo.2025.1563944 · Frontiers in Endocrinology · 2025-04-28

## TL;DR

The study found that longer nap durations are linked to a higher risk of having both hypertension and diabetes in minority populations in China.

## Contribution

This study is the first to explore the association between nap duration and hypertension-diabetes comorbidity in minority populations using the CMEC dataset.

## Key findings

- Longer nap durations were associated with increased odds of hypertension-diabetes comorbidity.
- The relationship between nap duration and comorbidity varied by age group, showing linear and inverse J-shaped patterns.
- Subgroup analyses revealed higher risk in males, older individuals, and specific ethnic groups.

## Abstract

Limited information is available on the effect of nap duration and hypertension-diabetes comorbidity (HDC) in minority people. We aimed to explore the relationship between nap duration and HDC for the co-management of hypertension and diabetes mellitus in the minority.

A total of 16,911 participants from the China Multi-Ethnic Cohort (CMEC) were enrolled in this cross-sectional study. Nap duration was then categorized into four groups: 0 hours (reference group), 0–0.5 hours, 0.5–1 hour, and >1 hour. Multiple logistic regression was applied to analyze the association between nap duration and HDC. Restricted cubic splines (RCS) analysis was conducted to assess the nonlinear relationship between nap duration and the co-occurrence of HDC. Subgroup analyses were subsequently performed, stratified by sex, age, and ethnicity.

Among 16,911 participants with a median age of 51.79 years, of whom 66.00% were female. A total of 647 subjects were in the HDC group, representing a prevalence rate of 3.83% in the entire study population. Multivariate logistic regression analysis showed that, after multivariate adjustments, the odds ratios (95% CI) for HDC across the four groups (0h, 0–0.5h, 0.5–1h and > 1h) were: reference, 1.305 (1.027, 1.650), 1.254 (1.016, 1.542), 1.612 (1.261, 2.046), respectively. RCS analyses revealed distinct associations between naptime duration and HDC: no significant relationship in participants aged <45 years (P-overall=0.529); a linear positive correlation in those aged 45–60 years (P-overall=0.001); and an inverse J-shaped association peaking at 60 minutes in individuals aged >60 years (P-overall=0.026, P-nonlinearity=0.015). The subgroup analysis revealed that among >45 years, male, Dong or Miao, a longer nap duration was also associated with an increased prevalence risk of HDC.

Longer napping duration were associated with an increased risk of HDC and monitoring nap duration may aid in identifying high-risk groups.

## Linked entities

- **Diseases:** diabetes mellitus (MONDO:0005015)
- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** hypertension (MESH:D006973), diabetes (MESH:D003920)
- **Chemicals:** Nap (MESH:C043186)

## Full text

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## Figures

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## References

47 references — full list in the complete paper: https://tomesphere.com/paper/PMC12066342/full.md

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Source: https://tomesphere.com/paper/PMC12066342