# A Rare Presentation of Sclerosing-Type Rhabdomyosarcoma in an Underserved Patient: A Case Report

**Authors:** Lorena Rivera, Delaram Pourkalbassi, Desiree Boisson, Nick Taylor, Ernest Metelus, Ammaar Jan, Oudhay S Sohal, Damian Casadesus

PMC · DOI: 10.7759/cureus.82110 · Cureus · 2025-04-11

## TL;DR

A 40-year-old man with no prior medical history was diagnosed with a rare form of rhabdomyosarcoma after presenting with leg swelling, but he was lost to follow-up and returned with metastatic disease.

## Contribution

This case report highlights a rare presentation of sclerosing-type rhabdomyosarcoma in an underserved patient.

## Key findings

- The patient was diagnosed with high-grade rhabdomyosarcoma with sclerosing features.
- The patient was lost to follow-up and returned with metastatic disease.
- The case emphasizes challenges in managing cancer in underserved populations.

## Abstract

A man in his early 40s, with no previous medical history, presented to the emergency room with right leg swelling. It had started more than one month prior to the presentation, but the patient had not sought medical attention due to lack of insurance. He underwent an ultrasound, computed tomography (CT) scan, and magnetic resonance imaging (MRI). The studies revealed a mass in the right vastus medialis muscle. A biopsy revealed a high-grade rhabdomyosarcoma (RMS) with sclerosing features. The patient started treatment with vincristine, actinomycin D, and ifosfamide (VAI). He continued chemotherapy as an outpatient, but was lost to follow-up. He returned four months later with metastatic disease.

## Linked entities

- **Chemicals:** vincristine (PubChem CID 5978), actinomycin D (PubChem CID 457193), ifosfamide (PubChem CID 3690)
- **Diseases:** rhabdomyosarcoma (MONDO:0005212)

## Full-text entities

- **Diseases:** RMS (MESH:D012208), swelling (MESH:D004487)
- **Chemicals:** ifosfamide (MESH:D007069), VAI (MESH:C064227), actinomycin D (MESH:D003609), vincristine (MESH:D014750)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12066213/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12066213/full.md

## References

11 references — full list in the complete paper: https://tomesphere.com/paper/PMC12066213/full.md

---
Source: https://tomesphere.com/paper/PMC12066213