# A Case Report of Celiac Disease and Small Bowel Adenocarcinoma: Two Diseases With Similar Symptoms

**Authors:** Ana Oliveira, Gisela Gonçalves, Bárbara Paracana, Laura Baptista, Tatiana Rodrigues

PMC · DOI: 10.7759/cureus.82086 · Cureus · 2025-04-11

## TL;DR

This case report highlights a patient with celiac disease who later developed small bowel adenocarcinoma, emphasizing the need for cancer screening in symptomatic celiac patients.

## Contribution

The paper presents a rare case linking celiac disease and small bowel adenocarcinoma, emphasizing the importance of cancer screening in symptomatic patients.

## Key findings

- A patient with celiac disease developed small bowel adenocarcinoma one year after diagnosis.
- Symptomatic celiac patients should be screened for neoplasms, especially after a gluten-free diet fails to alleviate symptoms.

## Abstract

Celiac disease (CD) is an autoimmune disease triggered by gluten in the diet. The association between CD and increased risk of neoplasia is described mainly in patients diagnosed with CD and aged over 40 years or during the first years after CD diagnosis. Patients who remain symptomatic after 12 months of gluten-free diet should be screened to exclude neoplasms, especially lymphoma and gastrointestinal neoplasms. We report a case of small bowel adenocarcinoma (SBA) in a patient diagnosed with CD one year earlier.

## Linked entities

- **Diseases:** Celiac disease (MONDO:0005130), small bowel adenocarcinoma (MONDO:0003198)

## Full-text entities

- **Diseases:** gastrointestinal neoplasms (MESH:D005770), lymphoma (MESH:D008223), SBA (MESH:D000230), autoimmune disease (MESH:D001327), CD (MESH:D002446), neoplasia (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12066094/full.md

## References

8 references — full list in the complete paper: https://tomesphere.com/paper/PMC12066094/full.md

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Source: https://tomesphere.com/paper/PMC12066094