# Idiopathic Granulomatous Appendicitis: A Case Report and Review of the Literature

**Authors:** Abanoub Awad, Isaac Theerman, Jason Beckermann

PMC · DOI: 10.7759/cureus.82081 · Cureus · 2025-04-11

## TL;DR

A 30-year-old woman was diagnosed with a rare form of appendicitis after surgery and tests ruled out other causes.

## Contribution

This case highlights the importance of accurate diagnosis to prevent unnecessary surgery in idiopathic granulomatous appendicitis.

## Key findings

- The patient's symptoms and imaging were consistent with acute appendicitis.
- Histopathology confirmed granulomatous appendicitis without Crohn's disease or infection.
- IGA has a favorable prognosis after appendectomy.

## Abstract

Idiopathic granulomatous appendicitis (IGA) is a rare condition that clinically presents similar to acute appendicitis, with symptoms such as abdominal pain, fever, and anorexia. We report a case of a 30-year-old postpartum female who presented with symptoms of acute appendicitis. Imaging revealed a thickened appendix, and laparoscopic appendectomy was performed. Intraoperative findings led to conversion to laparotomy with ileocolic resection. Histopathology confirmed granulomatous appendicitis with focal suppuration and no evidence of Crohn's disease or infection. IGA is diagnosed by excluding other infectious or non-infectious causes, and appendectomy is the treatment of choice, with a favorable prognosis. The condition requires careful pathological evaluation to avoid unnecessary extensive surgery.

## Linked entities

- **Diseases:** acute appendicitis (MONDO:0005649), Crohn's disease (MONDO:0005011)

## Full-text entities

- **Diseases:** fever (MESH:D005334), Crohn's disease (MESH:D003424), abdominal pain (MESH:D015746), infection (MESH:D007239), anorexia (MESH:D000855), IGA (MESH:D001064)

## Full text

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## Figures

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## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12066088/full.md

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Source: https://tomesphere.com/paper/PMC12066088