# Hydroa Vacciniforme: A Rare Pediatric Photodermatosis

## TL;DR

This paper describes a rare skin condition in a child caused by a virus and managed with sun protection.

## Contribution

The study presents a new clinical case of hydroa vacciniforme with detailed diagnostic and management insights.

## Key findings

- The patient showed chronic photodermatosis linked to Epstein-Barr virus infection.
- Strict photoprotection led to sustained remission over two years.
- Histopathology and immunohistochemistry confirmed characteristic lymphoid infiltrates and EBV involvement.

## Abstract

Hydroa vacciniforme (HV) is a rare, chronic photodermatosis linked to Epstein-Barr virus (EBV) infection. We report a 12-year-old child with recurrent vesiculobullous facial lesions and photosensitivity for six years. Clinical examination revealed hemorrhagic crusts with atrophic scars. Dermoscopy showed whitish streaks and rosettes. Histopathology demonstrated epidermal spongiosis and a dense dermal lymphoid infiltrate. Immunohistochemistry confirmed CD3+, CD5+, CD7+, and CD8+ lymphocytes, with granzyme B and perforin expression, but no CD56. EBV serology was positive. Differential diagnoses, including cutaneous lupus, leishmaniasis, and porphyria, were excluded. The patient was managed with strict photoprotection, leading to sustained remission over two years. Early diagnosis and sun protection are essential for managing HV, as seen in our case.