# A Solitary Pedunculated Nevus Lipomatosus Superficialis

**Authors:** Julia S Murphy, John J Fowler, Morteza Khodaee

PMC · DOI: 10.7759/cureus.82040 · Cureus · 2025-04-10

## TL;DR

A woman in her 40s had a large, irritating skin lesion on her back that was diagnosed as a rare condition called nevus lipomatosus superficialis after a biopsy.

## Contribution

This case report highlights the importance of biopsy in diagnosing symptomatic pedunculated skin lesions.

## Key findings

- A symptomatic pedunculated skin lesion was diagnosed as nevus lipomatosus superficialis via excisional biopsy.
- Large pedunculated skin lesions, though often benign, should be biopsied if causing symptoms.
- The case emphasizes the need for clinical evaluation and histopathological confirmation in such rare presentations.

## Abstract

Large pedunculated skin lesions are a rare presentation in primary care settings. In general, these lesions are asymptomatic other than occasional irritation and discomfort. Although differential diagnosis mainly includes benign lesions, an excisional biopsy should be performed, particularly in symptomatic cases. We present the case of a woman in her 40s with an irritating large and pedunculated skin lesion on her back. Due to the symptomatic nature of the lesion, an excisional biopsy was performed, which confirmed the diagnosis of a nevus lipomatosus superficialis.

## Full-text entities

- **Diseases:** skin lesion (MESH:D012871), Nevus Lipomatosus Superficialis (MESH:C564368)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12065967/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12065967/full.md

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Source: https://tomesphere.com/paper/PMC12065967