# A Rare Presentation of NEC and High Grade IVH in a Near-Term, Normal Weight Baby With Positive Thrombophilia Profile: Case Report

**Authors:** Maria Amr, Raja Imad Abu Iram, Ehab Mohammad Abuawwad, Iyad Zuhair Jabari, Areen H. Qunaibi, Walaa Altamimi, Ahmad Abu Sharkh

PMC · DOI: 10.1155/crpe/8889033 · Case Reports in Pediatrics · 2025-05-02

## TL;DR

A near-term, normal weight baby developed NEC and high-grade IVH, which are typically seen in preterm infants, and was found to have a positive thrombophilia profile.

## Contribution

This case report highlights a rare occurrence of NEC and IVH in a near-term, normal weight infant with thrombophilia.

## Key findings

- NEC and high-grade IVH occurred in a near-term, normal weight baby without typical risk factors.
- The infant was found to have a positive thrombophilia profile upon investigation.

## Abstract

Necrotizing enterocolitis (NEC) is a serious condition characterized by severe ischemic inflammation of the bowel with invasion of gas-forming organisms into the bowel wall. Intraventricular hemorrhage (IVH) is another serious condition characterized by bleeding into the ventricles from the friable germinal matrix in premature infants. Both typically occur in the preterm and low–birth weight neonates. In this report, we present a 36+-week gestation and normal weight newborn with no risk factors developed both NEC and high-grade IVH. Upon investigation, he was found to have a positive thrombophilia profile.

## Linked entities

- **Diseases:** Necrotizing enterocolitis (MONDO:0004639), thrombophilia (MONDO:0002305)

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), NEC (MESH:D020345), Thrombophilia (MESH:D019851), ischemic (MESH:D002545), inflammation (MESH:D007249), IVH (MESH:D000074042)

## Full text

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## Figures

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## References

23 references — full list in the complete paper: https://tomesphere.com/paper/PMC12064310/full.md

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Source: https://tomesphere.com/paper/PMC12064310