# Reoperative Aortic Root Replacement in Patients with Prior Aortic Valve, Root Replacement, or Arch Replacement Surgery: A Single-Center Experience

**Authors:** Toyokazu Endo, Jaimin R. Trivedi, Priyadarshini Chandrashekhar, Michele Gallo, Erin M. Schumer, Biran Ganzel, Mark S. Slaughter, Siddharth Pahwa

PMC · DOI: 10.1055/a-2542-4443 · AORTA Journal · 2025-04-08

## TL;DR

This study examines the outcomes of reoperative aortic root replacement in patients who had prior aortic surgeries, finding a 10.9% perioperative mortality rate.

## Contribution

The study provides a single-center experience on reoperative aortic root replacement in patients with prior aortic surgeries.

## Key findings

- Perioperative mortality was 10.9% (6 patients) in the study.
- Common inpatient complications included prolonged ventricular support and bleeding events.
- Indications for reoperation included valvular stenosis, endocarditis, aneurysm, and dissection.

## Abstract

This case series evaluated the characteristics and outcomes of reoperative root replacement in patients with prior aortic valve replacement (AVR), aortic root replacement (ARR), or ascending or hemiarch replacement (AoR) from our single institution from 2014 to 2023. A total of 55 (prior surgery: 38 AVR, 5 ARR, and 12 AoR) patients were identified and indication for reoperation included valvular stenosis, endocarditis, aneurysm, and dissection. Perioperative mortality was 10.9% (6 patients) (inpatient complications: 2 stroke, 4 bleeding event, 2 renal failure, and 21 prolonged vent).

## Linked entities

- **Diseases:** endocarditis (MONDO:0005025)

## Full-text entities

- **Diseases:** endocarditis (MESH:D004696), renal failure (MESH:D051437), valvular stenosis (MESH:D011666), stroke (MESH:D020521), bleeding (MESH:D006470), aneurysm (MESH:D000783)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12061486/full.md

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Source: https://tomesphere.com/paper/PMC12061486