# Genetic diversity and phylogeny of avian orthoreovirus isolates from Peruvian broiler chickens

**Authors:** Doris Villanueva-Pérez, Luis Tataje-Lavanda, Angela Montalván-Avalos, Gisela Isasi-Rivas, Diego Paredes-Inofuente, Suly Montoya-Ortiz, Manolo Fernández-Sánchez, Eliana Icochea, Manolo Fernández-Díaz

PMC · DOI: 10.1128/mra.00054-25 · Microbiology Resource Announcements · 2025-04-04

## TL;DR

This study examines the genetic diversity of avian orthoreovirus in Peruvian broiler chickens and identifies three main genotypes.

## Contribution

The study provides new insights into the genetic classification of avian orthoreovirus isolates in Peru.

## Key findings

- Avian orthoreovirus isolates were grouped into genotypes 1, 2, and 3 based on σC gene analysis.
- The findings highlight the need for further research to improve vaccination strategies against the virus.

## Abstract

Avian orthoreovirus infections are increasingly common in Peruvian broiler chickens, primarily causing arthritis/tenosynovitis syndrome. In this study, sequencing and phylogenetic analysis of the σC gene revealed that avian orthoreovirus isolates were clustered in genotypes 1, 2, and 3. However, further research is needed to understand its genetic diversity and improve vaccination strategies.

## Linked entities

- **Genes:** ERMAP (erythroblast membrane associated protein (Scianna blood group)) [NCBI Gene 114625]

## Full-text entities

- **Genes:** sigma-C (sigma-C protein) [NCBI Gene 10220429]
- **Diseases:** tenosynovitis syndrome (MESH:D013717), Avian orthoreovirus infections (MESH:D001715), arthritis/ (MESH:D001168)
- **Species:** Gallus gallus (bantam, species) [taxon 9031]

## Full text

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## Figures

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12060683/full.md

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Source: https://tomesphere.com/paper/PMC12060683